54979-73-6Relevant articles and documents
Synthesis and biological relationships of 3′,6-substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives as antimitotic agents
Lai, Ya-Yun,Huang, Li-Jiau,Lee, Kuo-Hsiung,Xiao, Zhiyan,Bastow, Kenneth F.,Yamori, Takao,Kuo, Sheng-Chu
, p. 265 - 275 (2007/10/03)
As part of a continuing search for potential anticancer drug candidates in the 2-phenyl-4-quinolone series, 3′,6-substituted 2-phenyl-4-quinolone-3- carboxylic acid derivatives and their salts were synthesized and evaluated. Preliminary screening showed t
Diazotisation Rearrangement of Tosylhydrazones of ortho- and meta-Substituted-benzophenones and α-Substituted-acetophenones (Synthesis of Anilides)
Joshi, Vidya,Sharma, R. K.
, p. 564 - 566 (2007/10/02)
Ortho and meta-substituted-benzophenones (1a-g) and substituted-acetophenones (1h-i) were converted into tosylhydrazones (2a-i) by reacting with p-toluenesulphonyl-hydrazide.Conversion of 2a-i to the anilides (3a-i) was effected with the reagents H2SO4 and NaNO2, and was found to be as facile as in case of the para-substituted-benzophenone hydrozones.