7515-73-3

Basic information

• Product Name: 4-(chlorophenylmethyl)-1,1'-biphenyl
• Synonyms: 4-(chlorophenylmethyl)-1,1'-biphenyl;4-(A-CHLOROBENZYL)BIPHENYL;4-(Bisphenyl)chlorophenylmethane;4-(-Chlorobenzyl)biphenyl
• CAS NO: 7515-73-3
• Molecular Formula: C₁₉H₁₅Cl
• Molecular Weight: 278.7754
• EINECS: 231-369-8
• Mol File: 7515-73-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(chlorophenylmethyl)-1,1'-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(chlorophenylmethyl)-1,1'-biphenyl(7515-73-3)
• EPA Substance Registry System: 4-(chlorophenylmethyl)-1,1'-biphenyl(7515-73-3)

Safety Data

• Hazardous Substances Data: 7515-73-3(Hazardous Substances Data)

Usage

General Description

4-(chlorophenylmethyl)-1,1'-biphenyl is a chemical compound with the molecular formula C19H15Cl. It is a biphenyl derivative with a chlorophenylmethyl group attached to one of the phenyl rings. 4-(chlorophenylmethyl)-1,1'-biphenyl is commonly used as a building block in organic synthesis and is known for its potential applications in the field of pharmaceuticals and material science. It is also used in the production of advanced electronic materials and as a key intermediate in the synthesis of various biologically active compounds. The chemical structure of 4-(chlorophenylmethyl)-1,1'-biphenyl makes it a versatile and important compound in the development of new drugs and materials.

Upstream product

• 7598-80-3 4-phenylbenzhydrol 
• 2128-93-0 biphenyl-4-yl-phenyl-methanone 
• 7647-01-0 hydrogenchloride 
• 3218-36-8 4-Phenylbenzaldehyde 
• 96042-30-7 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran 
• 100-59-4 phenylmagnesium chloride 
• 613-42-3 4-benzylbiphenyl 

Downstream Products

• 982-45-6 1-phenyl-3-phenyl-3-(4-phenylphenyl)-1-propyne 
• 33240-59-4 2,3,5,6,2',3',4',5',6'-Nonachloro-4-(chloro-pentachlorophenyl-methyl)-biphenyl 
• 19773-28-5 4-(methoxy(phenyl)methyl)-1,1′-biphenyl 
• 982-46-7 4-(1,3-diphenylpropa-1,2-dien-1-yl)-1,1'-biphenyl 
• 60628-96-8 bifonazole 
• 60778-89-4 1-[(1,1-biphenyl)-4-yl-phenylmethyl]-1H-1,2,4-triazole 

Relevant articles and documents

Visible Light-Catalyzed Benzylic C-H Bond Chlorination by a Combination of Organic Dye (Acr+-Mes) and N-Chlorosuccinimide

By combining "N-chlorosuccinimide (NCS)"as the safe chlorine source with "Acr+-Mes"as the photocatalyst, we successfully achieved benzylic C-H bond chlorination under visible light irradiation. Furthermore, benzylic chlorides could be converted to benzylic ethers smoothly in a one-pot manner by adding sodium methoxide. This mild and scalable chlorination method worked effectively for diverse toluene derivatives, especially for electron-deficient substrates. Careful mechanistic studies supported that NCS provided a hydrogen abstractor "N-centered succinimidyl radical,"which was responsible for the cleavage of the benzylic C-H bond, relying on the reducing ability of Acr?-Mes.

Synthesis, antibacterial and antifungal activities of bifonazole derivatives

Two series of chlorinated benzhydryl imidazole and triazole derivatives were synthesized and tested in vitro against representative strains of potent pathogenic bacteria (Staphylococcus aureus CIP 4.83, Escherichia hirae CIP 5855, Pseudomonas aeruginosa CIP 82118, Escherichia coli CIP 53126) and fungi (Aspergillus niger IP 1431.83, Candida albicans IP 48.72, Candida krusei IP 208.52, Trichophython rubrum IP 1657.86). Most of these compounds were devoid of any antimicrobial activity, but several of them inhibited T. rubrum with MIC values in the range of 0.125 to 32 μg/mL, similar or superior to those of bifonazole and clotrimazole, used as standard controls. The replacement of the imidazole ring with a triazole moiety in these compounds led to derivatives with less antifungal activity. A preliminary SAR was undertaken on the effect of the number and the position of chlorine atoms on the distribution of negative charge on the surface of some compounds on antifungal activity. Copyright

Biocidal benzylbiphenyl derivatives

This invention concerns compounds of formula. stereochemically isomeric forms thereof, acid or base addition salts thereof, N-oxides thereof, or quaternary ammonium derivatives thereof, wherein the dotted line is an optional bond; X is a direct bond when the dotted line represents a bond, or X is hydrogen or hydroxy, when the dotted line does not represent a bond; R1, R2, R5and R6are each independently selected from hydrogen, halo, hydroxy, C1-4alkyl, C1-4alkyloxy, —SO3H, and the like; R3and R4are each independently selected from hydrogen, halo, hydroxy, C1-4alkyl, C1-4alkyloxy, nitro, amino, cyano, trifluoromethyl, or trifluoromethoxy;L is a radical of formula wherein A1is a direct bond or C1-6alkanediyl; A2is C2-6alkanediyl; and R7to R11are hydrogen, C1-6alkyl, aminoC1-6alkyl and the like; having biocidal properties; their preparation, compositions containing them and their use as a biocide.