7598-80-3

Basic information

• Product Name: alpha-phenyl[1,1'-biphenyl]-4-methanol
• Synonyms: alpha-phenyl[1,1'-biphenyl]-4-methanol;A-PHENYL-1,1BIPHENYL-4-METHANOL;4-PHENYLBENZHYDROL;(1,1'-Biphenyl-4-yl)phenylmethanol;Phenyl(biphenyl-4-yl)methanol;α-(4-Biphenylyl)benzyl alcohol;α-Phenyl[1,1'-biphenyl]-4-methanol;α-Phenylbiphenyl-4-methanol
• CAS NO: 7598-80-3
• Molecular Formula: C₁₉H₁₆O
• Molecular Weight: 260.32974
• EINECS: 231-506-1
• Mol File: 7598-80-3.mol
• Article Data: 51

Chemical Properties

• Boiling Point: 435.6 °C at 760 mmHg
• Flash Point: 180.6 °C
• Appearance: /
• Density: 1.12 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: alpha-phenyl[1,1'-biphenyl]-4-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: alpha-phenyl[1,1'-biphenyl]-4-methanol(7598-80-3)
• EPA Substance Registry System: alpha-phenyl[1,1'-biphenyl]-4-methanol(7598-80-3)

Safety Data

• Hazardous Substances Data: 7598-80-3(Hazardous Substances Data)

Usage

General Description

Alpha-phenyl[1,1'-biphenyl]-4-methanol, also known as 4-phenyldiphenylmethanol, is an organic compound with the chemical formula C19H16O. It is a white crystalline solid with a slight odor, and is insoluble in water but soluble in organic solvents such as ethanol and ether. alpha-phenyl[1,1'-biphenyl]-4-methanol is commonly used as a building block in the synthesis of various pharmaceuticals and organic materials. Its unique chemical structure, featuring a benzene ring attached to a biphenyl group, makes it a valuable intermediate for the production of a wide range of specialty chemicals. Additionally, alpha-phenyl[1,1'-biphenyl]-4-methanol exhibits potential pharmacological properties and has been studied for its potential use in drug development.

Upstream product

• 64-17-5 ethanol 
• 2128-93-0 biphenyl-4-yl-phenyl-methanone 
• 1068-55-9 isopropylmagnesium chloride 
• 60-29-7 diethyl ether 
• 927-77-5 n-propylmagnesium bromide 
• 71-43-2 benzene 
• 13224-48-1 meso-1,2-bis-biphenyl-4-yl-1,2-diphenyl-ethane-1,2-diol 
• 141-52-6 sodium ethanolate 
• 30905-13-6 4-biphenylylphenyldiazomethane 
• 14845-83-1 4-biphenylphenylcarbene 
• 3218-36-8 4-Phenylbenzaldehyde 
• 683-60-3 sodium isopropylate 
• 104-88-1 4-chlorobenzaldehyde 
• 98-80-6 phenylboronic acid 

Downstream Products

• 19773-28-5 4-(methoxy(phenyl)methyl)-1,1′-biphenyl 
• 7515-73-3 4-(chlorophenylmethyl)-1,1'-biphenyl 
• 60047-92-9 4-phenyl-benzhydryl bromide 
• 613-42-3 4-benzylbiphenyl 
• 136908-18-4 2-[1-(Biphenyl-4-yl-phenyl-methoxy)-ethyl]-naphthalene 
• 2128-93-0 biphenyl-4-yl-phenyl-methanone 
• 324-74-3 4-fluoro-biphenyl 
• 162824-36-4 1-<α-(4-Biphenylyl)benzyl>imidazole-4,5-dicarbonitrile 
• 60778-89-4 1-[(1,1-biphenyl)-4-yl-phenylmethyl]-1H-1,2,4-triazole 
• 7732-18-5 water 
• 693272-62-7 2-[4-(biphenyl-4-yl-phenyl-methoxy)-butoxy]-tetrahydro-pyran 

Relevant articles and documents

Heterocyclic carbene complexes of nickel, palladium, and copper(I) as effective catalysts for the reduction of ketones

Carbene complexes of nickel, palladium, and copper(I) effectively catalyze the reduction of aromatic ketones under the influence of 2-propanol in the presence of potassium hydroxide. Bis(1,3-dimethyl-benzimidazol-2-ylidene)copper(I) iodide and the polymeric complex of crown-biscarbene with copper(I) iodide show the highest catalytic efficiency.

Gold-Catalyzed Oxidative Biaryl Cross-Coupling of Organometallics

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Heterobimetallic Complexes Bridged by Imidazol{[4,5- f][1,10]-phenanthrolin}-2-ylidene: Synthesis and Catalytic Activity in Tandem Reactions

A series of monometallic complexes obtained by metalation of the phenanthrolin donor in 1,3-dibutyl-1H-imidazol[4,5-f][1,10]phenanthrolin}ium hexafluorophospate 1 (M = Pd 2, Ru 3, Ir 4) have been prepared. Subsequently, the imidazolium moiety of complexes 2-4 was metalated with M′, leading to the heterobimetallic phenanthroline/NHC complexes (M/M′ = Pd/Rh 5, Pd/Ir 6, Pd/Ru 7, Ru/Pd 8, Ir/Pd 9) and the homobimetallic complex (M/M′ = Ir/Ir 10). The new complexes were characterized by elemental analysis, FTIR, UV-vis, and NMR spectroscopy. The molecular structures of the heterobimetallic complexes 5 and 6 were determined by X-ray diffraction studies. The catalytic activity of the heterobimetallic complexes 5-9 were tested in selected tandem reactions (dehalogenation/transfer hydrogenation and Suzuki-Miyaura coupling/transfer hydrogenation). It was found that the M/M′ heterobimetallic complexes display higher catalytic activities when compared to equimolar mixtures of the mononuclear complexes M and M′, thus indicating that an increase in the number of metal atoms in one complex leads to an increased activity in the tandem reactions.