7544-64-1 Usage
General Description
2,4-Dimethyl-[1,8]naphthyridine is a chemical compound with the molecular formula C14H12N2. It is a member of the naphthyridine class of compounds, which are known for their diverse biological activities. 2,4-Dimethyl-[1,8]naphthyridine has been investigated for its potential pharmaceutical properties, including as an anti-inflammatory and anti-cancer agent. It has also been studied for its potential application in organic electronic devices due to its unique electronic and optical properties. 2,4-DIMETHYL-[1,8]NAPHTHYRIDINE is currently of interest to researchers in the fields of medicinal chemistry, organic synthesis, and materials science for its potential applications in a variety of fields.
Check Digit Verification of cas no
The CAS Registry Mumber 7544-64-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,5,4 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 7544-64:
(6*7)+(5*5)+(4*4)+(3*4)+(2*6)+(1*4)=111
111 % 10 = 1
So 7544-64-1 is a valid CAS Registry Number.
7544-64-1Relevant articles and documents
Regioselective addition of n-alkyllithiums to α,α′- disubstituted-1,8-naphthyridines: Synthesis of 6-amino-3-pyridinol analogs of α-tocopherol
Nam, Tae-Gyu,Wijtmans, Maikel,Pratt, Derek A.,Porter, Ned A.
, p. 1397 - 1404 (2005)
n-Alkyllithiums were added to α,α′-disubstituted-1,8- naphthyridines in non-polar solvents such as Et2O-hexane mixtures. In polar solvents such as THF, alkyllithium acts as a base rather than a nucleophile. Regioselective addition was achieved for substrates capable of five-membered cyclic chelation of the (alkyl)lithium reagent. Substrates with a TBS-protected alcohol as the co-chelating moiety afforded the best combination of yield and regioselectivity. This methodology was successfully employed in the preparation of two 6-amino-3-pyridinol analogs of pentamethyl-chromanol (PMC), an a-tocopherol derivative with its isoprenoid side chain truncated to a methyl group. Georg Thieme Verlag Stuttgart.
