77223-21-3

Basic information

• Product Name: 7-CHLORO-2,4-DIMETHYL-[1,8]NAPHTHYRIDINE
• Synonyms: 7-CHLORO-2,4-DIMETHYL-[1,8]NAPHTHYRIDINE
• CAS NO: 77223-21-3
• Molecular Formula: C₁₀H₉ClN₂
• Molecular Weight: 192.64
• Mol File: 77223-21-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 305°C at 760 mmHg
• Flash Point: 166.9°C
• Appearance: /
• Density: 1.246g/cm³
• Vapor Pressure: 0.00152mmHg at 25°C
• Refractive Index: 1.627
• CAS DataBase Reference: 7-CHLORO-2,4-DIMETHYL-[1,8]NAPHTHYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-CHLORO-2,4-DIMETHYL-[1,8]NAPHTHYRIDINE(77223-21-3)
• EPA Substance Registry System: 7-CHLORO-2,4-DIMETHYL-[1,8]NAPHTHYRIDINE(77223-21-3)

Safety Data

• Hazardous Substances Data: 77223-21-3(Hazardous Substances Data)

Usage

General Description

7-CHLORO-2,4-DIMETHYL-[1,8]NAPHTHYRIDINE is a chemical compound with a naphthyridine structure that contains a chloro and two methyl groups. It is used in the pharmaceutical industry as a building block for the synthesis of various drug compounds. This chemical exhibits potent antimicrobial and anti-inflammatory properties, making it a valuable ingredient in the development of new medications for the treatment of infections and inflammatory conditions. Additionally, 7-CHLORO-2,4-DIMETHYL-[1,8]NAPHTHYRIDINE may also have potential applications in agricultural and veterinary products as a pesticide or antibacterial agent. Its unique structure and functional properties make it a versatile and important chemical in the fields of medicine and agriculture.

InChI:InChI=1/C10H9ClN2/c1-6-5-7(2)12-10-8(6)3-4-9(11)13-10/h3-5H,1-2H3

Upstream product

• 51420-71-4 5,7-dimethyl-1,8-naphthyridin-2(1H)-one 
• 141-86-6 2.6-diaminopyridine 
• 39565-07-6 7-amino-2,4-dimethyl-1,8-naphthyridine 
• 123-54-6 acetylacetone 
• 51420-71-4 2-hydroxyl-5,7-dimethyl-1,8-naphthyridine 
• 27224-55-1 C₉H₁₀N₄ 
• 17884-12-7 C₉H₉N₃O 

Downstream Products

• 7544-64-1 2,4-dimethyl[1,8]naphthyridine 
• 65541-95-9 5,7-dimethyl-1,2,3,4-tetrahydro[1,8]naphthyridine 
• 91860-11-6 2-[(5,7-Dimethyl-[1,8]naphthyridin-2-yl)-(2-hydroxy-ethyl)-amino]-ethanol 
• 144101-82-6 7-diphenylphosphino-2,4-dimethyl-1,8-naphthyridine 
• 958231-59-9 2-[N-(2,4-dimethyl-1,8-naphthyridyl)]amino-5,7-dimethyl-1,8-naphthyridin-7-yl 
• 958231-61-3 2-[N-(2-pyridyl)methyl]amino-5,7-dimethyl-1,8-naphthyridine 
• 1025726-26-4 2,4-dimethyl-7-p-tolyl-1,8-naphthyridine 

Relevant articles and documents

1,8-naphthyridine modified naphthalimide derivative: Ratiometric and selective sensor for hg2+ in organic aqueous solution

A bottom-modified (4-position) naphthalimide derivative 1 with 1,8-naphthyridine as binding site has been designed and synthesized. Compound 1 is the first 1,8-naphthyridine-modified naphthalimide-based sensor that can detect Hghg2+ selectively with respect to ratiometric fluorescent change and blue shift in organic aqueous solution. The Job's plot and FAB mass indicate that 1 formed a 1:1 complex with Hg2+. A top-modified naphthalimide derivative 2 with 1,8-naphthyridin as binding site has also been synthesized for comparison.

Substituted 1,8-naphthyridines, their preparation and their use as antidotes

A combination of a variety of herbicides with safening agents which are substituted 1,8-naphthyridines of the formula STR1 where R1 is mercapto, hydroxyl, halogen, benzylthio, amino or NR2 R3, where R2 is a grou