769167-55-7 Usage
Description
(S)-2-(cyclopentyloxycarbonylaMino)non-8-enoic acid, with the molecular formula C15H25NO4, is a non-essential amino acid derivative that plays a significant role in the biosynthesis of the neurotransmitter acetylcholine. This chemical compound is also recognized for its potential pharmaceutical applications, particularly in the development of anti-inflammatory and anti-tumor drugs. Its unique structure and properties make it a valuable tool in the study of biological processes and drug discovery.
Uses
Used in Pharmaceutical Industry:
(S)-2-(cyclopentyloxycarbonylaMino)non-8-enoic acid is used as a key compound in the development of anti-inflammatory and anti-tumor drugs due to its potential pharmaceutical applications. Its role in the biosynthesis of acetylcholine, a neurotransmitter, makes it a promising candidate for the treatment of various diseases and conditions related to inflammation and tumor growth.
Used in Research and Development:
(S)-2-(cyclopentyloxycarbonylaMino)non-8-enoic acid is utilized as a valuable tool in the research and development of new therapeutic agents. Its unique structure and properties allow scientists to study biological processes and drug discovery, contributing to the advancement of medical treatments for a wide range of diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 769167-55-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,9,1,6 and 7 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 769167-55:
(8*7)+(7*6)+(6*9)+(5*1)+(4*6)+(3*7)+(2*5)+(1*5)=217
217 % 10 = 7
So 769167-55-7 is a valid CAS Registry Number.
769167-55-7Relevant articles and documents
A concise synthesis of the HCV protease inhibitor BILN 2061 and its P3 modified analogs
Liu, Dejun,Dong, Jingchao,Yin, Yunxing,Ma, Rujian,Shi, Yifeng,Wu, Hao,Chen, Shuhui,Li, Ge
, p. 1489 - 1502 (2011/11/01)
A concise synthesis of BILN 2061 was achieved through more efficient installation of P2 4-quinoline moiety via SN2 displacement of the β-OBs group located on the 4-hydroxyl proline intermediate, which was prepared from 4-α-hydroxyl proline analog via Mitsunobu reaction with inversion of stereochemistry. In addition, a short and practical synthesis for P3 unit is also described herein. Final assembly of four fragments for BILN 2061 was achieved with an overall yield of 58% in 4 steps from P1 to 15a. Furthermore several analogs of BILN 2061 (WX-1-WX-5) containing modifications on P3 unit were synthesized successfully using the same synthetic route as described for the parent inhibitor BILN 2061. Copyright
Efficient synthesis of (S)-2-(cyclopentyloxycarbonyl)-amino-8-nonenoic acid: Key building block for BILN 2061, an HCV NS3 protease inhibitor
Wang, Xiao-Jun,Zhang, Li,Smith-Keenan, Lana L.,Houpis, Ioannis N.,Farina, Vittorio
, p. 60 - 63 (2012/12/26)
A new procedure for the practical synthesis of (S)-2-(cyclopen- tyloxycarbonyl)amino-8-nonenoic acid, a key building block for BILN 2061, an HCV NS3 protease inhibitor, has been developed. The key step features a kinetic resolution of racemic 2-acetylamino-8-nonenoic acid with acylase I. In addition, the undesired (R)-2-acetylamino-8-nonenoic acid was recycled after racemization. The procedure was implemented for the production of (S)-2-(cyclopentyloxycarbonyl)amino-8-nonenoic acid on pilot-plant scale.
