881683-81-4 Usage
Description
(S)-ethyl 2-(tert-butoxycarbonylamino)non-8-enoate is an ester compound with a molecular structure derived from non-8-enoic acid and (S)-ethyl 2-amino propanoate. It is commonly used as a building block in organic synthesis and medicinal chemistry to create more complex molecules. The tert-butoxycarbonyl (Boc) protecting group is attached to the amino group to prevent unwanted reactions during synthesis, making it a versatile and stable component in the development of various bioactive molecules.
Uses
Used in Organic Synthesis:
(S)-ethyl 2-(tert-butoxycarbonylamino)non-8-enoate is used as a building block for creating more complex organic molecules, particularly in the field of medicinal chemistry. Its stability and ease of manipulation during chemical reactions make it a valuable component in the synthesis of a wide range of compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (S)-ethyl 2-(tert-butoxycarbonylamino)non-8-enoate is used as a key intermediate in the preparation of peptides and other bioactive molecules. The Boc protecting group allows for controlled deprotection and functionalization, facilitating the synthesis of targeted therapeutic agents.
Used in Research and Development:
(S)-ethyl 2-(tert-butoxycarbonylamino)non-8-enoate is also utilized in research and development for the exploration of new chemical reactions and the design of novel bioactive compounds. Its unique structure and functional groups make it an attractive candidate for studying various reaction mechanisms and developing innovative synthetic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 881683-81-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,1,6,8 and 3 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 881683-81:
(8*8)+(7*8)+(6*1)+(5*6)+(4*8)+(3*3)+(2*8)+(1*1)=214
214 % 10 = 4
So 881683-81-4 is a valid CAS Registry Number.
881683-81-4Relevant articles and documents
CALPAIN MODULATORS AND METHODS OF PRODUCTION AND USE THEREOF
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, (2017/09/27)
The present technology relates to compounds, kits, compositions, and methods useful for the treatment of fibrotic disease. In some aspects, the present technology provides for treatment of various diseases or disorders associated or mediated, at least in part, by calpains, such as CAPN1, CAPN2, and/or CAPN9. The present technology is generally applicable to compounds which inhibit myofibroblast differentiation.
Interaction of aliphatic cap group in inhibition of histone deacetylases by cyclic tetrapeptides
Nishino, Norikazu,Shivashimpi, Gururaj M.,Soni, Preeti B.,Bhuiyan, Mohammed P.I.,Kato, Tamaki,Maeda, Satoko,Nishino, Tomonori G.,Yoshida, Minoru
, p. 437 - 445 (2008/09/16)
Inhibitors of histone deacetylases (HDACs) are a promising class of anticancer agents that effect gene regulation. To know the interaction of aliphatic cap groups with HDACs, cyclic tetrapeptide and bicyclic peptide disulfide hybrids were synthesized without aromatic ring in their macrocyclic framework. Benzene ring of l-Phe in chlamydocin was replaced with several aliphatic amino acids and also a fused bicyclic tetrapeptide was synthesized by ring closing metathesis using Grubb's first generation catalyst. The inhibitory activities of the cyclic peptides against histone deacetylase enzymes were evaluated, which demonstrated most of them are interesting candidates as anticancer agents.
