80817-34-1Relevant articles and documents
NUCLEOSIDES AND NUCLEOTIDES. PART 27. SOLID PHASE SYNTHESIS OF A TRIDECANUCLEOSIDE DODECAPHOSPHATE CONTAINING THE UNNATURAL BASE 4-AMINO-2(1H)-PYRIDINONE AND OF AN OCTANUCLEOSIDE HEPTAPHOSPHATE FOR THE DETERMINATION OF THE DNA-POLYMERASE SPECIFICITY
Charczuk, Roland,Tamm, Cristoph
, p. 717 - 725 (2007/10/02)
The tridecanucleoside dodecaphosphate d-(T-T-Z-C-G-T-C-A-A-A-A-T-C) incorporating the modified nucleoside 4-amino-1-(2'-deoxy-β-ribofuranosyl)-2(1H)-pyridone (Zd, 1) and the octanucleoside heptaphosphate d(G-A-T-T-T-T-G-A) were synthesized by the solid-phase method using the triester method.The carrier material was a copolymer consisting of styrene with 1 percent divinylbenzene.
ON THE PHOSPHORYLATION OF DEOXYRIBONUCLEOSIDES AND THE PROTECTION OF DEOXYGUANOSINE
Francois, P.,Hamoir, G.,Sonveaux, E.,Vermeersch, H.,Ma, Y.
, p. 821 - 824 (2007/10/02)
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Improved Synthesis of Oligodeoxyribonucleotides by Solid-Phase Phosphotriester Method Utilizing O6--2'-deoxyguanosine Derivatives
Chollet, Andre,Ayala, Edgar,Kawashima, Eric H.
, p. 1356 - 1364 (2007/10/02)
The synthesis of oligodeoxyribonucleotides on a cross-linked polystyrene solid support utilizing stable mono- and dinucleotide phosphotriester building blocks is presented.The use of O6--2'deoxyguanosine derivatives yields cleaner DNA fragments by supressing side reactions.Modifications improving the phosphotriester methodology are presented.The purification methods and analysis of synthetic oligodeoxyribonucleotides are described.