83977-12-2

Basic information

• Product Name: 1,3-Dioxolane, 2-(2-phenylethenyl)-, (E)-
• CAS NO: 83977-12-2
• Molecular Formula: C11H12O2
• Molecular Weight: 176.215
• Mol File: 83977-12-2.mol
• Article Data: 54

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxolane, 2-(2-phenylethenyl)-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxolane, 2-(2-phenylethenyl)-, (E)-(83977-12-2)
• EPA Substance Registry System: 1,3-Dioxolane, 2-(2-phenylethenyl)-, (E)-(83977-12-2)

Safety Data

• Hazardous Substances Data: 83977-12-2(Hazardous Substances Data)

Upstream product

• 52509-14-5 (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide 
• 100-52-7 benzaldehyde 
• 64847-78-5 (E)-1,1-diacetoxy-3-phenylprop-2-ene 
• 3590-59-8 2,2-dibutyl[1,3,2]dioxastannolane 
• 100-51-6 benzyl alcohol 
• 104-55-2 3-phenyl-propenal 
• 107-21-1 ethylene glycol 
• 646-06-0 1,3-DIOXOLANE 
• 637-44-5 phenylpropyolic acid 
• 103-64-0 bromostyrene 
• 4392-24-9 Cinnamyl bromide 
• 1402750-99-5 S-methyl-S-phenyl-N-cinnamylsulfoximine 
• 1402750-74-6 (E)-S-phenyl-S-vinyl-N-cinnamylsulfoximine 
• 14371-10-9 (E)-3-phenylpropenal 

Downstream Products

• 110777-39-4 2-bromoethyl trans-cinnamate 
• 104-55-2 3-phenyl-propenal 
• 623-91-6 diethyl Fumarate 
• 141-05-9 Diethyl maleate 
• 1515-78-2 buta-1,3-dien-1-ylbenzene 
• 26958-41-8 cinnamyl-1,3-dithiane 
• 146604-63-9 2-hydroxyethyl 3-(phenyl)-2-propenoate 
• 55337-55-8 2-(2-oxo-2-phenyl-ethyl)-1,3-dioxolane 
• 100058-84-2 2-(2'-hydroxy-2'-phenyl)ethyl-1,3-dioxolane 
• 14371-10-9 (E)-3-phenylpropenal 

Relevant articles and documents

Synthesis and cytotoxic properties of some cyclic acetals of diols and their dichlorocyclopropyl derivatives

Cyclic acetals of ethylene glycol, cis-but-2-ene-1,4-diol and their dichlorocyclopropyl derivatives were synthesized. Compounds simultaneously containing the gem-dichlorocyclopropane and 1,3-dioxacycloalkane cycles are shown to exhibit cytotoxic activity against the HEK293, SH-SY5Y, HepG2, MCF-7, A549, and Jurkat cell lines. The obtained results open up prospects for further studies of antitumor activity of 2-(2,2-dichlorocyclopropyl)-2-ethyl-1,3-dioxolane.

Photoredox Oxo-C(sp3)-H Bond Functionalization via in Situ Cu(I)-Acetylide Catalysis

A unified strategy for the synthesis of 2-vinyl heterocycles is reported. With visible light irradiation, simple and cheap CuCl is able to functionalize a terminal alkyne, giving Cu(I)-acetylide in situ. Unlike the case of noble metals or organic dye photocatalysts, this critical Cu(I)-acetylide not only activates the C-H bond of terminal alkynes but also serves as a photocatalyst to achieve varieties of 2-vinyl heterocycles in good to excellent yields, even for large scale and late-stage functionalization of natural product.

NiCl2-catalyzed radical cross decarboxylative coupling between arylpropiolic acids and cyclic ethers

A direct alkenylation of cyclic ethers via radical cross decarboxylative coupling process catalyzed by NiCl2 and using DTBP as radical initiator and oxidant was developed. A variety of arylpropiolic acids and cyclic ethers were transformed into the corresponding 2-arylvinyl cyclic ethers in moderate to excellent yields. Mechanistic experiments were conducted to determine the nature of the reaction intermediates, and a plausible reaction mechanism involving NiCl2-promoted radical process was proposed.