85612-59-5

Basic information

• Product Name: (2R)-3-PHENYL-1,2-PROPANEDIAMINE
• Synonyms: (2R)-3-PHENYL-1,2-PROPANEDIAMINE;(2R)-3-Pheny-1,2-propanediamine;(R)-3-Phenyl-1,2-propanediamine
• CAS NO: 85612-59-5
• Molecular Formula: C₉H₁₄N₂
• Molecular Weight: 150.22
• Product Categories: Chemical Amines;Amines;Aromatics;Chiral Reagents
• Mol File: 85612-59-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 66-75°C / ~0.1-0.5 Torr
• Flash Point: 148.8°C
• Appearance: /
• Density: 1.025g/cm³
• Vapor Pressure: 0.00291mmHg at 25°C
• Refractive Index: 1.561
• Storage Temp.: Refrigerator, Under Inert Atmosphere
• CAS DataBase Reference: (2R)-3-PHENYL-1,2-PROPANEDIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-3-PHENYL-1,2-PROPANEDIAMINE(85612-59-5)
• EPA Substance Registry System: (2R)-3-PHENYL-1,2-PROPANEDIAMINE(85612-59-5)

Safety Data

• Hazardous Substances Data: 85612-59-5(Hazardous Substances Data)

Usage

Chemical Properties

Clear Colourless Liquid

InChI:InChI=1/C9H14N2/c10-7-9(11)6-8-4-2-1-3-5-8/h1-5,9H,6-7,10-11H2/t9-/m1/s1

Upstream product

• 5241-58-7 D-Phenylalaninamide 
• 673-06-3 D-(R)-phenylalanine 
• 13033-84-6 D-phenylalanine methyl ester hydrochloride 
• 190839-76-0 (2R)-tert-butyl-(2-azidomethyl-1-benzylethyl) carbamate 
• 130406-33-6 (R)-α-(azidomethyl)-2-phenylethanamine 
• 5267-64-1 (R)-2-amino-3-phenylpropanol 
• 106454-69-7 N-tert-butoxycarbonyl-D-Phenylalaninol 
• 126301-19-7 (2R)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate 
• 5241-58-7 L-Phenylalanine amide 
• 63-91-2 L-phenylalanine 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 

Downstream Products

• 1096689-99-4 (R)-4-Benzyl-4,5-dihydro-1H-imidazole 
• 1438881-27-6 (R)-3-phenyl-N₁-(2-pyridin-4-yl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)propane-1,2-diamine 

Relevant articles and documents

6-O-SUBSTITUTED KETOLIDES HAVING ANTIBACTERIAL ACTIVITY

PROBLEM TO BE SOLVED: To provide 6-O-substituted ketolides with antibacterial activity, having acid stability and enhanced activity toward gram negative bacteria and macrolide resistant gram positive bacteria. SOLUTION: This invention provides 6-O-substituted erythromycin ketolide derivatives such as formula (II) and compositions comprising the compounds. [Y and Z together form a group X; X is ketone, hydroxyimino or the like; or, one of Y and Z is H and the other is hydrogen, hydroxy or the like; Ra is H, hydroxy; Rc is H or a hydroxy protective group; R is a substituted methyl group]. COPYRIGHT: (C)2015,JPOandINPIT

Macrolide antiinfective agents

The invention is directed towards antibacterial compounds. The invention concerns macrolide antibiotics useful as antiinfective agents.

6-O-substituted ketolides having antibacterial activity

Antimicrobial compounds having the formula STR1 as well as pharmaceutically acceptable salts, esters or prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of the compounds.