87100-61-6Relevant articles and documents
Evaluation of heteroatom-rich derivatives as antitubercular agents with InhA inhibition properties
Moulkrere, Bachar Rébat,Orena, Beatrice S.,Mori, Giorgia,Saffon-Merceron, Nathalie,Rodriguez, Frédéric,Lherbet, Christian,Belkheiri, Nadji,Amari, Mohamed,Hoffmann, Pascal,Fodili, Mokhtar
, p. 308 - 320 (2018/04/19)
Two series of heterocyclic compounds derived from 3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one (DHA) and 2-acetylbutyrolactone have been synthesized and characterized. The compounds were evaluated for their activities against Mycobacterium tuberculosis stra
1,4-Disubstituted-5-hydroxy-3-methylpyrazoles and some derived ring systems as cytotoxic and DNA binding agents. Synthesis, in vitro biological evaluation and in silico ADME study
Hany Badr, Mona,Abd El Razik, Heba Attia
, p. 442 - 457 (2017/09/27)
Some novel polysubstituted pyrazoles, bipyrazoles and pyranopyrazoles, supported with various chemotherapeutically-active pharmacophores, were synthesized and biologically evaluated for their cytotoxic potential. Fifteen compounds (7–9, 12, 16, 17, 19, 21
Synthesis of some pyrano[2,3-c]pyrazoles
Pavlik, James W.,Ervithayasuporn, Vuthichai,Tantayanon, Supawan
, p. 710 - 714 (2011/07/31)
Synthetic methods have been developed to prepare pyrano[2,3-c]pyrazoles with various substituents at ring positions 1, 3, and 6. The 1H- and 13C-NMR properties of these products and their precursors are presented and discussed.