88196-06-9

Basic information

• Product Name: syn-1-phenylpropane-1,2-diol
• Synonyms: syn-1-phenylpropane-1,2-diol
• CAS NO: 88196-06-9
• Molecular Weight: 152.193
• Mol File: 88196-06-9.mol
• Article Data: 101

Chemical Properties

• CAS DataBase Reference: syn-1-phenylpropane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: syn-1-phenylpropane-1,2-diol(88196-06-9)
• EPA Substance Registry System: syn-1-phenylpropane-1,2-diol(88196-06-9)

Safety Data

• Hazardous Substances Data: 88196-06-9(Hazardous Substances Data)

Upstream product

• 1846-29-3 1,3-diphenyl-2-methylpropane-1,3-dione 
• 4541-87-1 cis-1-phenylpropene oxide 
• 5650-40-8 (S)-2-hydroxypropiophenone 
• 14212-54-5 (+)-(R,R)-β-methylstyrene oxide 
• 71-43-2 benzene 
• 100-52-7 benzaldehyde 
• 873-66-5 1-propenylbenzene 
• 766-90-5 cis-1-phenyl-1-propylene 
• 91111-01-2 (R)-1-oxo-1-phenylpropan-2-yl acetate 
• 579-07-7 1-Phenylpropane-1,2-dione 
• 637-50-3 1-phenylpropene 
• 673-32-5 1-Phenylprop-1-yne 
• 75927-49-0 pinacol vinylboronate 
• 25438-37-3 phenyl(trimethylsiloxy)acetonitrile 

Downstream Products

• 145950-20-5 Acetic acid (1S,2R)-2-chloro-1-methyl-2-phenyl-ethyl ester 
• 145950-19-2 (1S,2S)-(-)-1-cyclohexylpropane-1,2-diol 
• 799246-07-4 (4S,5S)-4-methyl-5-phenyl-1,3,2-dioxathiolane-2-oxide 
• 420087-33-8 (2R,3R)-2-methyl-3-phenylaziridine 
• 61091-40-5 (-)-trans-(2S,3S)-2-methyl-3-phenylaziridin 
• 51-64-9 dexamfetamine 
• 156-34-3 l-amphetamine 
• 2323-36-6 SELEGILINE 
• 33817-09-3 (R)-2-methylamino-1-phenylpropane 
• 255060-78-7 (-)-(1R,2S)-1-azido-1-phenyl-2-propanol 
• 167083-50-3 (1S,2R)-1-azido-1-phenylpropane-2-ol 
• 145987-14-0 (2S,3S)-(-)-cyclohexyl-3-methyloxirane 
• 145950-26-1 Acetic acid (1S,2R)-2-chloro-2-cyclohexyl-1-methyl-ethyl ester 
• 145950-28-3 Acetic acid (1S,2R)-2-bromo-2-cyclohexyl-1-methyl-ethyl ester 

Relevant articles and documents

A Protocol for NMR Analysis of the Enantiomeric Excess of Chiral Diols Using an Achiral Diboronic Acid Template

A practically simple derivatization protocol for determining the enantiopurity of chiral diols by 1H NMR spectroscopic analysis is described. Diols were treated with 0.5 equiv of 1,3-phenyldiboronic acid to afford mixtures of diastereomeric boronate esters whose homochiral/heterochiral ratios are an accurate reflection of the diol's enantiopurity.

Enantioselective, Stereoconvergent Resolution Copolymerization of Racemic cis-Internal Epoxides and Anhydrides

Unprecedented enantioselective resolution copolymerization of racemic cis-internal epoxides and anhydrides was mediated by dinuclear aluminum complexes with multiple chirality, affording optically active polyesters with two contiguous stereogenic centers, and the unreacted substrates in good enantioselectivity. Unexpected stereoconvergence is observed in this resolution copolymerization, where the selectivity factor for the enantioselective formation of copolymer significantly exceeds the kinetic resolution coefficient based on the unreacted epoxide at various conversions. Catalytic activity and copolymer enantioselectivity are strongly influenced by the phenolate ortho-substituents of the ligand set, as well as the axial linker and its chirality. An enantiopure binaphthol-linked bimetallic AlIII complex allows stereoconvergent access to the stereoregular semi-crystalline polyesters and a concomitant kinetic resolution of the epoxide substrates.

Electrochemically Tuned Oxidative [4+2] Annulation and Dioxygenation of Olefins with Hydroxamic Acids

This work represents the first [4+2] annulation of hydroxamic acids with olefins for the synthesis of benzo[c][1,2]oxazines scaffold via anode-selective electrochemical oxidation. This protocol features mild conditions, is oxidant free, shows high regioselectivity and stereoselectivity, broad substrate scope of both alkenes and hydroxamic acids, and is compatible with terpenes, peptides, and steroids. Significantly, the dioxygenation of olefins employing hydroxamic acid is also successfully achieved by switching the anode material under the same reaction conditions. The study not only reveals a new reactivity of hydroxamic acids and its first application in electrosynthesis but also provides a successful example of anode material-tuned product selectivity.