89220-51-9

Basic information

• Product Name: 1-(1-BROMOMETHYL-VINYL)-4-CHLORO-BENZENE
• Synonyms: 1-(1-BROMOMETHYL-VINYL)-4-CHLORO-BENZENE;1-(3-Bromoprop-1-en-2-yl)-4-chlorobenzene
• CAS NO: 89220-51-9
• Molecular Formula: C₉H₈BrCl
• Molecular Weight: 231.51682
• Mol File: 89220-51-9.mol
• Article Data: 27

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(1-BROMOMETHYL-VINYL)-4-CHLORO-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-BROMOMETHYL-VINYL)-4-CHLORO-BENZENE(89220-51-9)
• EPA Substance Registry System: 1-(1-BROMOMETHYL-VINYL)-4-CHLORO-BENZENE(89220-51-9)

Safety Data

• Hazardous Substances Data: 89220-51-9(Hazardous Substances Data)

Usage

Chemical structure

1-(1-Bromomethyl-vinyl)-4-chloro-benzene consists of a benzene ring with a chlorine atom at the 4th position and a bromomethyl-vinyl group attached to the 1st position.

Bromomethyl-vinyl group

This group consists of a bromine atom bonded to a carbon, which is further bonded to a vinyl group, making it a halogenated alkene.

Halogenated alkene

The presence of a bromine atom in the vinyl group classifies the compound as a halogenated alkene.

Reactivity

The compound has a reactive vinyl group, which allows it to be used as a reagent in various chemical reactions.

Applications

It is commonly used in organic synthesis and can be used as a building block in the synthesis of more complex organic molecules.

Hazardous nature

The compound is potentially hazardous and should be handled with caution.

Controlled environment

It should be used in a controlled environment by trained professionals to ensure safety and proper handling.

Upstream product

• 1712-70-5 1-chloro-4-(1-methylethenyl)-benzene 
• 99-91-2 para-chloroacetophenone 
• 7732-18-5 water 
• 45941-96-6 2-(4-chlorophenyl)-3-hydroxypropene 
• 106-39-8 bromochlorobenzene 

Downstream Products

• 145949-83-3 N-<2-(4-chlorophenyl)prop-2-enyl>phthalimide 
• 127876-32-8 <2-(4-chlorophenyl)prop-2-enyl>amine 
• 843651-74-1 N-tert-butoxycarbonyl-N'-[2-(4-chlorophenyl)allyl]hydrazine 
• 769196-59-0 (2R,3S)-5-(4-chlorophenyl)hex-5-ene-1,2,3-triol 
• 769196-63-6 (2R,3S,5R)-5-(4-chlorophenyl)-tetrahydro-2-(hydroxymethyl)-5-(iodomethyl)furan-3-ol 
• 128665-97-4 3-amino-2-(4-chlorophenyl)-2-hydroxypropanesulfonic acid hydrochloride 
• 117354-64-0 2-hydroxysaclofen 
• 145949-88-8 N-<2-(4-chlorophenyl)prop-2-enyl>acetamide 
• 145949-87-7 N-<2-(4-chlorophenyl)-2,3-epoxypropyl>phthalimide 
• 145949-86-6 2-(4-chlorophenyl)-2-hydroxy-3-phthalimidopropanesulfonic acid 
• 897019-27-1 tert-butyl 4-(2-(4-chlorophenyl)prop-2-en-1-yl)piperazine-1-carboxylate 
• 1191271-44-9 2-[2-(4-chloro-phenyl)-allyloxy]-naphthalene-1-carbaldehyde 
• 1234835-80-3 N-(but-3-enyl)-N-(2-(4-chlorophenyl)allyl)-p-toluenesulfonamide 
• 1234835-99-4 5-(4-chlorophenyl)-1-p-toluenesulfonyl-1,2,3,6-tetrahydropyridine 

Relevant articles and documents

Copper-Catalyzed Enantiotopic-Group-Selective Allylation of gem-Diborylalkanes

We report a copper-catalyzed enatiotopic-group-selective allylation of gem-diborylalkanes with allyl bromides. The combination of copper(I) bromide and H8-BINOL derived phosphoramidite ligand proved to be the most effective catalytic system to provide various enantioenriched homoallylic boronate esters, containing a boron-substituted stereogenic center that is solely derived from gem-diborylalkanes, in good yields with high enantiomeric ratios under mild conditions. Experimental and theoretical studies have been conducted to elucidate the reaction mechanism, revealing how the enatiotopic-group-selective transmetalation of gem-diborylalkanes with chiral copper complex occurs to generate chiral α-borylalkyl-copper species for the first time. Additional synthetic applications to the synthesis of various chiral building blocks are also included.

Visible-light-promoted radical alkylation/cyclization of allylic amide with N-hydroxyphthalimide ester: Synthesis of oxazolines

An efficient photocatalytic alkylation/cyclization of allylic amide with N-hydroxyphthalimide ester has been developed. The transformation is taken advantage of alkyl radicals to attack allylic amide with the assist of inexpensive rose bengal as photocatalyst to prepare a series of alkyl substituted oxazolines in moderate to excellent yields. High regioselectivity, operational safety, mild conditions and excellent substrate generality give this protocol broad application prospects.

HETEROAROMATIC COMPOUNDS AS VANIN INHIBITORS

The present invention encompasses compounds of the formula I which are suitable for the treatment of diseases related to Vanin, and processes for making these compounds, pharmaceutical preparations containing these compounds, and their methods of use.