90172-72-8

Basic information

• Product Name: Benzenecarbothioic acid, 4-fluoro-, S-(phenylmethyl) ester
• CAS NO: 90172-72-8
• Molecular Formula: C14H11FOS
• Molecular Weight: 246.305
• Mol File: 90172-72-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzenecarbothioic acid, 4-fluoro-, S-(phenylmethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenecarbothioic acid, 4-fluoro-, S-(phenylmethyl) ester(90172-72-8)
• EPA Substance Registry System: Benzenecarbothioic acid, 4-fluoro-, S-(phenylmethyl) ester(90172-72-8)

Safety Data

• Hazardous Substances Data: 90172-72-8(Hazardous Substances Data)

Upstream product

• 1283075-99-9 dipropan-2-yl 1-(4-fluorobenzoyl)hydrazine-1,2-dicarboxylate 
• 100-53-8 phenylmethanethiol 
• 459-57-4 4-fluorobenzaldehyde 
• 201230-82-2 carbon monoxide 
• 459-45-0 4-fluorobenzenediazonium tetrafluoroborate 
• 16601-02-8 S-benzyl 4-methylbenzenethiosulfonate 
• 100-39-0 benzyl bromide 
• 456-22-4 4-Fluorobenzoic acid 
• 100-44-7 benzyl chloride 
• 403-43-0 4-fluorobenzoyl chloride 

Relevant articles and documents

Palladium Catalyzed Direct Carbonylative Thiomethylation of Aryldiazonium Salts and Amines with 4-(Methylthio)-2-Butanone as (Methylthio) Transfer Agent

Herein, an interesting palladium-catalyzed procedure for the direct carbonylative thiomethylation of aromatic amine derivatives with 4-methylthio-2-butanone is developed. Using 4-methylthio-2-butanone as (methylthio) transfer agent, a variety of corresponding thioesters are obtained with moderate to good yields under base-free condition. In addition, good functional group tolerance can be observed.

Organocatalytic Transformation of Aldehydes to Thioesters with Visible Light

A metal- and oxidant-free catalytic method for accessing structurally diverse thioesters from readily accessible, widespread aldehydes, is described. A strategy of a simple organic 9,10-phenanthrenequinone-promoted hydrogen atom transfer (HAT) with visible light was successfully implemented to selectively generate acyl radicals without inducing crossover reactivity of thioester products. The preparative power of the method was demonstrated by broad substrate scope and wide functional group tolerance, and enabled the late-stage modification of complex structures, which are difficult to achieve with the existing protocols.

A facile, one-pot procedure for the conversion of aromatic aldehydes to esters, as well as thioesters and amides, via acyl hydrazide intermediates

Herein we present an efficient method for the synthesis of esters from aromatic aldehydes via readily accessible acyl hydrazides. The developed reaction protocol is shown to be tolerant of a range of aromatic aldehydes, bearing various functionalities, as well as being amenable to the synthesis of thioesters and amides.