910114-64-6

Basic information

• Product Name: Carbamic acid, [[[[[(4-fluorophenyl)methyl]amino]carbonyl]amino](methylthio)methylene]- , methyl ester
• CAS NO: 910114-64-6
• Molecular Formula: C12H14FN3O3S
• Molecular Weight: 299.326
• Mol File: 910114-64-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [[[[[(4-fluorophenyl)methyl]amino]carbonyl]amino](methylthio)methylene]- , methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [[[[[(4-fluorophenyl)methyl]amino]carbonyl]amino](methylthio)methylene]- , methyl ester(910114-64-6)
• EPA Substance Registry System: Carbamic acid, [[[[[(4-fluorophenyl)methyl]amino]carbonyl]amino](methylthio)methylene]- , methyl ester(910114-64-6)

Safety Data

• Hazardous Substances Data: 910114-64-6(Hazardous Substances Data)

Upstream product

• 910114-63-5 methyl N-({[(4-fluorobenzen-1-yl)methyl]amino}carbonyl)carbamimidothioate 
• 79-22-1 methyl chloroformate 
• 132740-43-3 4-fluorobenzylisocyanate 

Downstream Products

• 910114-66-8 3-(4-fluorobenzyl)-1-(4-methoxybenzyl)-6-(methylthio)-1,3,5-triazine-2,4(1H,3H)-dione 
• 910114-67-9 6-(2-aminoethylamino)-3-(4-fluorobenzyl)-1-(4-methoxybenzyl)-1,3,5-triazine-2,4(1H,3H)-dione 
• 910114-79-3 [5-(4-fluoro-benzyl)-1-(4-methoxy-benzyl)-4,6-dioxo-1,4,5,6-tetrahydro-[1,3,5]triazin-2-ylamino]-acetic acid 
• 911368-93-9 3-(4-fluoro-benzyl)-6-methylsulfanyl-1H-[1,3,5]triazine-2,4-dione hydrochloride 
• 910114-06-6 N-{2-[5-(4-fluoro-benzyl)-1-(4-methoxy-benzyl)-4,6-dioxo-1,4,5,6-tetrahydro-[1,3,5]triazin-2-ylamino]-ethyl}-N'-amino-guanidine 
• 910114-65-7 3-(4-fluorobenzyl)-6-(methylthio)-1,3,5-triazine-2,4(1H,3H)-dione 

Relevant articles and documents

PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN

Disclosed are compounds, compositions and methods for treating pain, including inflammatory, visceral, and acute pain. Such compounds are represented by Formula (I) as follows: wherein A1, L1, D, L2, and Q are defined herein.

Triazinediones as prokineticin 1 receptor antagonists. Part 1: SAR, synthesis and biological evaluation

A series of guanidine triazinediones were identified as potent PK1 receptor antagonists. A compound in this series inhibited the PK1 invoked prosecretory response in rat ileum tissue.

PYRIMIDINDIONE DERIVATIVES AS PROKINETICIN 2 RECEPTOR ANTAGONISTS

The present invention relates to certain novel compounds of Formula (I), which are suitable for the treatment of prokineticin 2 or prokinetin 2 receptor mediated disorders.