92367-11-8 Usage
Description
4-[3-(TrifluoroMethyl)-3H-diazirin-3-yl]benzyl BroMide, also known as 3-[4-(Bromomethyl)phenyl]-3-(trifluoromethyl)diazirine, is a chemical compound with a unique structure that features a diazirine ring and a trifluoromethyl group. 4-[3-(TrifluoroMethyl)-3H-diazirin-3-yl]benzyl BroMide is known for its reactivity and is commonly used in synthetic chemistry for the preparation of various organic compounds.
Uses
Used in Pharmaceutical Industry:
4-[3-(TrifluoroMethyl)-3H-diazirin-3-yl]benzyl BroMide is used as a reactant in the synthetic preparation of ginkgolide derivatives incorporating fluorescent and photoactivatable groups. These derivatives are essential for photolabeling studies, which help researchers understand the molecular mechanisms of drug action and develop new therapeutic agents.
Used in Research and Development:
In the field of research and development, 4-[3-(TrifluoroMethyl)-3H-diazirin-3-yl]benzyl BroMide is utilized as a key intermediate in the synthesis of various organic compounds with potential applications in different industries. Its unique reactivity allows chemists to explore new synthetic routes and develop innovative molecules with desired properties.
Used in Chemical Synthesis:
4-[3-(TrifluoroMethyl)-3H-diazirin-3-yl]benzyl BroMide is employed as a versatile building block in chemical synthesis, particularly for the preparation of complex organic molecules. Its ability to undergo various chemical reactions makes it a valuable tool for chemists working on the development of new compounds with specific functions and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 92367-11-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,3,6 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 92367-11:
(7*9)+(6*2)+(5*3)+(4*6)+(3*7)+(2*1)+(1*1)=138
138 % 10 = 8
So 92367-11-8 is a valid CAS Registry Number.
92367-11-8Relevant articles and documents
Engineering bromodomains with a photoactive amino acid by engaging 'Privileged' tRNA synthetases
Wagner, Shana,Sudhamalla, Babu,Mannes, Philip,Sappa, Sushma,Kavoosi, Sam,Dey, Debasis,Wang, Sinan,Islam, Kabirul
supporting information, p. 3641 - 3644 (2020/04/07)
Site-specific placement of unnatural amino acids, particularly those responsive to light, offers an elegant approach to control protein function and capture their fleeting 'interactome'. Herein, we have resurrected 4-(trifluoromethyldiazirinyl)-phenylalan
Photoactivatable probes and uses thereof
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Page/Page column 17; 26, (2018/09/21)
Provided herein are pyridyl- and pyrimidyl-containing diazirines that can be photoactivateable probes and formulations thereof. Also provided herein are photoaffinity labels that can include the pyridyl- and pyrimidyl-containing diazirines provided herein. Also provided herein are methods of using the photoactivatable probes and photoaffinity labels provided herein in a photoaffinity labeling reaction and/or assay.
Rapid Mapping of Protein Interactions Using Tag-Transfer Photocrosslinkers
Horne, Jim E.,Walko, Martin,Calabrese, Antonio N.,Levenstein, Mark A.,Brockwell, David J.,Kapur, Nikil,Wilson, Andrew J.,Radford, Sheena E.
supporting information, p. 16688 - 16692 (2018/11/27)
Analysing protein complexes by chemical crosslinking-mass spectrometry (XL-MS) is limited by the side-chain reactivities and sizes of available crosslinkers, their slow reaction rates, and difficulties in crosslink enrichment, especially for rare, transie
