92398-61-3

Basic information

• Product Name: Cyclobutanecarboxylic acid, 1-[[1,4-dioxo-4-(phenylmethoxy)-2-[[(phenylmethoxy)carbonyl]amino]but yl]amino]-, methyl ester, (S)-
• CAS NO: 92398-61-3
• Molecular Formula: C25H28N2O7
• Molecular Weight: 468.507
• Mol File: 92398-61-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Cyclobutanecarboxylic acid, 1-[[1,4-dioxo-4-(phenylmethoxy)-2-[[(phenylmethoxy)carbonyl]amino]but yl]amino]-, methyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclobutanecarboxylic acid, 1-[[1,4-dioxo-4-(phenylmethoxy)-2-[[(phenylmethoxy)carbonyl]amino]but yl]amino]-, methyl ester, (S)-(92398-61-3)
• EPA Substance Registry System: Cyclobutanecarboxylic acid, 1-[[1,4-dioxo-4-(phenylmethoxy)-2-[[(phenylmethoxy)carbonyl]amino]but yl]amino]-, methyl ester, (S)-(92398-61-3)

Safety Data

• Hazardous Substances Data: 92398-61-3(Hazardous Substances Data)

Upstream product

• 22264-50-2 1-aminocyclobutane-1-carboxylic acid 
• 89691-88-3 1,3-diazaspiro[4.3]octane-2,4-dione 
• 123640-88-0 (S)-3-Benzyloxycarbonylamino-4-isobutoxycarbonyloxy-4-oxo-butyric acid benzyl ester 
• 92398-47-5 1-aminocyclobutane-1-carboxylic acid methyl ester hydrochloride 
• 3479-47-8 Z-Asp(OBzl)-OH 

Relevant articles and documents

Peptide Sweeteners. 6. Structural Studies on the C-Terminal Amino Acid of L-Aspartyl Dipeptide Sweeteners

Stereochemical and structural aspects of the variations in the C-terminal residue of L-aspartyl-L-phenylalanine methyl ester have been investigated.Novel configurational analogues such as L-aspartyl-D-alanine benzyl ester and L-aspartyl-D-α-aminobutyric acid benzyl ester were found to be sweet.In addition, chiral and achiral α,α-dialkylglycine and α-aminocycloalkanecarboxylic acids were incorporated into the dipeptides.The L-aspartic acid based dipeptide derivatives of α-aminoisobutyric acid methyl ester, α-aminocyclopropanecarboxylic acid methyl ester, α-aminocyclobutanecarboxylic acid methyl ester, and α-aminocyclopentanecarboxylic acid methyl ester are sweet.Dipeptides with α-aminocyclohexanecarboxylic acid methyl ester and α-aminocycloheptanecarboxylic acid methyl ester are bitter, whereas the analogues with α-aminocyclooctanecarboxylic acid methyl ester, α,α-diethylglycine methyl ester, and α-aminoisobutyric acid benzyl ester are tasteless.Aspects on chirality and effective volume of the C-terminal residue are discussed and correlated with taste.