929613-61-6

Basic information

• Product Name: Benzoic acid, 2-[2-[(3,4-difluorophenyl)thio]acetyl]-, methyl ester
• CAS NO: 929613-61-6
• Molecular Formula: C16H12F2O3S
• Molecular Weight: 322.332
• Mol File: 929613-61-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-[2-[(3,4-difluorophenyl)thio]acetyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-[2-[(3,4-difluorophenyl)thio]acetyl]-, methyl ester(929613-61-6)
• EPA Substance Registry System: Benzoic acid, 2-[2-[(3,4-difluorophenyl)thio]acetyl]-, methyl ester(929613-61-6)

Safety Data

• Hazardous Substances Data: 929613-61-6(Hazardous Substances Data)

Upstream product

• 1077-79-8 methyl 2-acetylbenzoate 
• 577-56-0 2-acetyl-benzoic acid 
• 85-44-9 phthalic anhydride 
• 60811-24-7 3,4-difluorobenzenethiol 
• 7460-55-1 2-(2-bromoacetyl)benzoic acid methyl ester 

Downstream Products

• 929613-69-4 1-(4-fluoro-3-trifluoromethylanilino)-4-(3,4-difluorophenylthiomethyl)phthalazine 
• 929613-70-7 1-(3,5-dichloroanilino)-4-(3,4-difluorophenylthiomethyl)phthalazine 
• 929613-76-3 1-chloro-4-(3,4-difluorophenyl)thiomethylphthalazine 
• 929613-63-8 1-hydroxy-4-(3,4-difluorophenyl)thiomethylphthalazine 

Relevant articles and documents

Synthesis and anticancer activities of novel 1,4-disubstituted phthalazines

A series of novel 1-anilino-4-(arylsulfanylmethyl)phthalazines were designed and synthesized. The structures of all the compounds were confirmed by IR, 1H-NMR, elemental analysis and MS. The analogues 1-(3-chloro-4-fluoroanilino)-4-(3,4-difluorophenylthio-methyl)phthalazine (12) and 1-(4-fluoro-3-trifluoromethylanilino)-4-(3,4-difluorophenyl-thiomethyl) phthalazine (13) showed higher activity than a cisplatin control when tested in vitro against two different cancer cell lines using the microculture tetrazolium method (MTT) method.