929613-69-4

Basic information

• Product Name: 1-Phthalazinamine, 4-[[(3,4-difluorophenyl)thio]methyl]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-
• CAS NO: 929613-69-4
• Molecular Formula: C22H13F6N3S
• Molecular Weight: 465.422
• Mol File: 929613-69-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Phthalazinamine, 4-[[(3,4-difluorophenyl)thio]methyl]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phthalazinamine, 4-[[(3,4-difluorophenyl)thio]methyl]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-(929613-69-4)
• EPA Substance Registry System: 1-Phthalazinamine, 4-[[(3,4-difluorophenyl)thio]methyl]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-(929613-69-4)

Safety Data

• Hazardous Substances Data: 929613-69-4(Hazardous Substances Data)

Upstream product

• 7460-55-1 2-(2-bromoacetyl)benzoic acid methyl ester 
• 929613-61-6 methyl 2-(2-(3,4-difluorophenylthio)acetyl)benzoate 
• 929613-63-8 1-hydroxy-4-(3,4-difluorophenyl)thiomethylphthalazine 
• 929613-76-3 1-chloro-4-(3,4-difluorophenyl)thiomethylphthalazine 
• 2357-47-3 4-Fluoro-3-trifluoromethylaniline 
• 1077-79-8 methyl 2-acetylbenzoate 
• 577-56-0 2-acetyl-benzoic acid 
• 85-44-9 phthalic anhydride 

Relevant articles and documents

Synthesis and anticancer activities of novel 1,4-disubstituted phthalazines

A series of novel 1-anilino-4-(arylsulfanylmethyl)phthalazines were designed and synthesized. The structures of all the compounds were confirmed by IR, 1H-NMR, elemental analysis and MS. The analogues 1-(3-chloro-4-fluoroanilino)-4-(3,4-difluorophenylthio-methyl)phthalazine (12) and 1-(4-fluoro-3-trifluoromethylanilino)-4-(3,4-difluorophenyl-thiomethyl) phthalazine (13) showed higher activity than a cisplatin control when tested in vitro against two different cancer cell lines using the microculture tetrazolium method (MTT) method.