94612-26-7

Basic information

• Product Name: 2-Azetidinone, 3-chloro-1-(4-methoxyphenyl)-4-phenyl-3-(phenylthio)-
• CAS NO: 94612-26-7
• Molecular Formula: C22H18ClNO2S
• Molecular Weight: 395.909
• Mol File: 94612-26-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-Azetidinone, 3-chloro-1-(4-methoxyphenyl)-4-phenyl-3-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azetidinone, 3-chloro-1-(4-methoxyphenyl)-4-phenyl-3-(phenylthio)-(94612-26-7)
• EPA Substance Registry System: 2-Azetidinone, 3-chloro-1-(4-methoxyphenyl)-4-phenyl-3-(phenylthio)-(94612-26-7)

Safety Data

• Hazardous Substances Data: 94612-26-7(Hazardous Substances Data)

Usage

Potential Applications

Medicinal chemistry
Pharmaceuticals
Materials science

Reactivity

Requires further research and experimentation to understand fully

Unique Properties

Complex structure offers potential for diverse reactivity and applications

Upstream product

• 84900-63-0 phenylthioglicolic acid potassium salt 
• 40339-42-2 4-methoxy-N-[(1Z)-phenylmethylene]aniline 
• 94612-48-3 1-(4-Methoxy-phenyl)-4-phenyl-3-phenylsulfanyl-azetidin-2-one 
• 104-94-9 4-methoxy-aniline 
• 100-52-7 benzaldehyde 
• 108-98-5 thiophenol 
• 783-08-4 [4-(benzylideneamino)phenyl]methanol 
• 1613-90-7 4-methoxy-N-[(E)-phenylmethylidene]aniline 
• 103-04-8 (phenylthio)acetic acid 
• 94612-48-3 trans-1-(4-methoxyphenyl)-4-phenyl-3-(phenylthio)azetidin-2-one 

Downstream Products

• 94612-33-6 1-(4-methoxyphenyl)-4-phenylazetidine-2,3-dione 
• 79114-06-0 cis-1-(4'-methoxyphenyl)-3-methoxy-4-phenylazetidin-2-one 

Relevant articles and documents

An unusual lewis acid promoted isomerization of trans-3-halo-3-phenylthio-β-lactams

A method for C-3 epimerization of 3-halo-3-phenylthio-β-lactams, mediated by Lewis acids, is described. TiCl4 promotes isomerization of trans-3-chloro-3-phenylthioazetidin-2-ones (2) to cis-3-chloro-3-phenylthioazetidin-2-ones (3). TiBr4/

Studies towards C-3 functionalization of β-lactams using substituted allylsilanes

An effective and stereoselective synthesis of 3-(1′-methyl/phenylallyl)-3-phenylthio-β-lactams (3/4) using substituted allylsilane and Lewis acid is described. The reaction leads to the formation of a mixture of C-3 substituted allyl β-Lactams.

C-3 β-lactam carbocation equivalents: versatile synthons for C-3 substituted β-lactams

An efficient and operationally simple strategy for the synthesis of differently C-3 monosubstituted (9) and disubstituted (10) monocyclic β-lactams is described. This involves reaction of β-lactam carbocation equivalents (8) with an active aromatic, aliph