95816-67-4Relevant articles and documents
A new catalytic application of a keggin acid in the synthesis of symmetrical bis(indolyl)alkanes
Chakrabarty, Manas,Mukherji, Ajanta,Karmakar, Sulakshana,Arima, Shiho,Harigaya, Yoshihiro
, p. 331 - 338 (2006)
Silicotungstic acid, H4SiW12O40, an important Keggin heteropoly acid, efficiently catalysed the reaction of indoles with aryl aldehydes in ethyl acetate solution at room temperature to furnish symmetrical bis(indolyl)alkanes expeditiously.
Triethylbenzylammonium chloride as a useful and efficient catalyst for the alkylation of indole/substituted indoles in water: A comparative study between conventional and microwave irradiation
Tumtina, Shokip,Kathing, Chingrishon,Phucho, Ivulho Tovishe,Nongrum, Ridaphun,Myrboh, Bekington,Nongkhlaw, Rishanlang
, p. 321 - 327 (2015/05/20)
A green and facile method for the alkylation of indole/substituted indole in water using a phase Transfer catalyst (Triethylbenzylammonium Chloride, TEBA) to synthesise bis-indolyl methanes (BIMs) and Michael addition of indole to α,β-unsaturated carbonyl compounds is reported. The substitution of indoles occurred exclusively at the 3-position and products of N-alkylation has not been observed. However, for 3-substituted indoles, reactions were found to occur at the 2-position. A comparative study between conventional heating and microwave irradiation has also been reported. A comparative study between conventional heating and microwave irradiation for the alkylation of indole/substituted indole in water using a phase transfer catalyst (Triethylbenzylammonium Chloride, TEBA) to synthesise bis-indolyl methanes (BIMs) and Michael addition of indole to α, β-unsaturated carbonyl compounds is reported.
Condensation of indoles and aldehydes in subcritical water without the addition of catalysts
Hirashita, Tsunehisa,Ogawa, Masaki,Hattori, Reina,Okochi, Sota,Araki, Shuki
supporting information, p. 1760 - 1764 (2016/01/27)
A series of 3,3′-diindolylmethanes were prepared in high yields from indoles and aldehydes under subcritical water conditions without the addition of catalysts. 3-Alkenylindoles were also obtained in good yields from aldehydes bearing benzylic hydrogen atoms.
