96354-74-4Relevant articles and documents
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Hall,Burckhalter
, p. 473 (1951)
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General synthesis of N-Alkylation of amines with secondary alcohols via hydrogen autotransfer
Subaramanian, Murugan,Midya, Siba P.,Ramar, Palmurukan M.,Balaraman, Ekambaram
supporting information, p. 8899 - 8903 (2019/11/14)
Direct catalytic N-alkylation of amines with secondary alcohols via hydrogen autotransfer (HA) strategy is very challenging and has been scarcely reported, even under precious metal catalysis. Herein, an efficient N-alkylation of amines, including benzyla
Efficient and practical catalyst-free-like dehydrative N-alkylation of amines and sulfinamides with alcohols initiated by aerobic oxidation of alcohols under air
Li, Xiaohui,Li, Shuangyan,Li, Qiang,Dong, Xu,Li, Yang,Yu, Xiaochun,Xu, Qing
supporting information, p. 264 - 272 (2015/12/30)
We developed simple and practical N-alkylation reactions of amines and sulfinamides with primary and secondary alcohols by using only catalytic amounts of air as the initiator without adding any external catalysts. This method has advantages of simple conditions, easy operation, and comparatively wider scope of substrates, providing an efficient and green catalyst-free-like alcohol-based dehydrative N-alkylation method. Mechanistic studies revealed that air initiated the reactions by aerobic oxidation of the alcohols to the key initiating aldehydes or ketones in the presence of bases.
