97273-03-5

Basic information

• Product Name: 2-Cyclohexyl-3-phenyl-1,2-thiazetidin-1,1-dioxid
• Synonyms: 2-Cyclohexyl-3-phenyl-1,2-thiazetidin-1,1-dioxid
• CAS NO: 97273-03-5
• Molecular Weight: 265.376
• Mol File: 97273-03-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Cyclohexyl-3-phenyl-1,2-thiazetidin-1,1-dioxid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexyl-3-phenyl-1,2-thiazetidin-1,1-dioxid(97273-03-5)
• EPA Substance Registry System: 2-Cyclohexyl-3-phenyl-1,2-thiazetidin-1,1-dioxid(97273-03-5)

Safety Data

• Hazardous Substances Data: 97273-03-5(Hazardous Substances Data)

Upstream product

• 97273-00-2 2-Cyclohexylamino-2-phenylethansulfonsaeure 
• 2039-44-3 sodium 2-phenylethylenesulfonate 
• 4091-26-3 β-styrenesulfonyl chloride 
• 108-91-8 cyclohexylamine 
• 167280-05-9 2-Cyclohexyl-4,4-dimethyl-3-phenyl-[1,2]thiazetidine 1,1-dioxide 

Downstream Products

• 21573-69-3 1-phenyl-1-cyclopentanecarboxaldehyde 
• 176696-63-2 (E)-2-Phenyl-1-trimethylsilanyl-ethenesulfonic acid cyclohexylamide 
• 56753-71-0 phenyl-propene-2-sulfonic acid amide 
• 64984-09-4 (E)-(2-phenylethenyl)sulfonamide 
• 13719-46-5 (E)-N-cyclohexyl-2-phenylethenesulfonamide 
• 210300-80-4 (E)-1-(tert-Butyl-dimethyl-silanyl)-2-phenyl-ethenesulfonic acid cyclohexyl-methyl-amide 
• 208395-41-9 2-Cyclohexyl-3-phenyl-4,4-bis-trimethylsilanyl-[1,2]thiazetidine 1,1-dioxide 
• 167280-05-9 2-Cyclohexyl-4,4-dimethyl-3-phenyl-[1,2]thiazetidine 1,1-dioxide 

Relevant articles and documents

Preparation of sulfonamides from sodium sulfonates: Ph3P·Br2 and Ph3P·Cl2 as a mild halogenating reagent for sulfonyl bromides and sulfonyl chlorides

Arene- and alkanesulfonamides were prepared by treatment of the corresponding sodium sulfonates with triphenylphosphine dibromide or dichloride followed by amines in the presence of triethylamine via sulfonyl halides. Reactions of sodium aminosulfonates gave cyclized products. Amidation of p-toluenesulfonic acid with triphenylphosphine dichloride was also examined to give N-benzyl-p-toluenesulfonamide. Methyl p- toluenesulfonate was obtained by esterification of sodium p-toluenesulfonate via p-toluenesulfonyl chloride.

Synthesis and Structure of 2,3-Disubstituted 1,2-Thiazetidine 1,1-Dioxides

2-Alkylamino-2-phenylethanesulfonic acids 3 are prepared from sodium 2-phenylethenesulfonate (2).Compounds 3 are chlorinated and cyclized to yield the title compounds 5.Their structures are characterized by IR and NMR spectroscopy and compared to those of analogous β-lactams.An X-ray analysis of the β-sultam 5d establishes the proposed structure.