97858-62-3 Usage
Description
(S,S)-DIPAMP, also known as (S,S)-1,2-bis(dimethylphosphino)ethane, is a chiral phosphine ligand that plays a crucial role in various chemical reactions. It is characterized by its two phosphino groups attached to a central carbon chain, with both phosphino groups having the same stereochemistry (S configuration). This unique structure allows it to act as a versatile and efficient catalyst in a wide range of applications.
Uses
Used in Pharmaceutical Industry:
(S,S)-DIPAMP is used as a catalyst for the preparation of diphosphinobenzenes, which are important intermediates in the synthesis of various pharmaceutical compounds. Its chiral nature ensures that the desired enantiomer is selectively formed, improving the purity and effectiveness of the final product.
Used in Chemical Industry:
(S,S)-DIPAMP is used as a catalyst in cross-coupling reactions, a class of chemical reactions that are widely employed in the synthesis of complex organic molecules. Its ability to selectively form desired products with high yields and selectivity makes it a valuable tool in the development of new materials and compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 97858-62-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,8,5 and 8 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 97858-62:
(7*9)+(6*7)+(5*8)+(4*5)+(3*8)+(2*6)+(1*2)=203
203 % 10 = 3
So 97858-62-3 is a valid CAS Registry Number.
InChI:InChI=1/C28H28O2P2/c1-29-25-17-9-11-19-27(25)31(23-13-5-3-6-14-23)21-22-32(24-15-7-4-8-16-24)28-20-12-10-18-26(28)30-2/h3-20H,21-22H2,1-2H3/t31-,32-/m0/s1
97858-62-3Relevant articles and documents
Preparation method of chiral 1, 2-bis [(2-methoxyphenyl) phenylphosphino] ethane
-
, (2022/04/06)
The invention discloses a preparation method of chiral 1, 2-bis [(2-methoxyphenyl) phenylphosphino] ethane, and belongs to the field of organic synthesis. According to the method, (2-methoxyphenyl) (phenyl) phosphine oxide chloride is used as an initial raw material; 2-methoxyphenyl) (phenyl) phosphine oxide lithium is prepared from 2-methoxyphenyl and metal lithium, then the 2-methoxyphenyl) (phenyl) phosphine oxide lithium reacts with 1, 2-dibromoethane to obtain racemic 1, 2-bis [(2-methoxyphenyl) phenylphosphine oxide] ethane, chiral 1, 2-bis [(2-methoxyphenyl) phenylphosphine oxide] ethane is obtained after chiral resolution, and finally trivalent chiral 1, 2-bis [(2-methoxyphenyl) phenylphosphine oxide] ethane is obtained through reduction. The invention relates to 1, 2-bis [(2-methoxyphenyl) phenylphosphino] ethane. Compared with the prior art, the method has the advantages of short reaction steps, simple operation and high yield, and is more suitable for industrial production. The prepared chiral 1, 2-bis [(2-methoxyphenyl) phenylphosphino] ethane is used as a ligand for chiral catalysis and is applied to the field of medicines.
Preparation method of chiral 1, 2-bis [(2-methoxyphenyl) phenylphosphino] ethane
-
Paragraph 0052; 0055-0056, (2020/07/28)
The invention discloses a preparation method of chiral 1, 2-bis [(2-methoxyphenyl) phenylphosphino] ethane, and belongs to the technical field of organic chemistry. The preparation method is carried out according to the following reaction path: the reacti
