Posaconazole, noxafil, posaconazol, voriconazole, CAS No. 171228-49-2

HANGZHOU HOLYPHARM BIOTECH CO.,LTD

Country:China (Mainland)

Year Established: 2009Business type: Other

Integral:

1. The description of Posaconazole

Posaconazole (CAS No. 171228-49-2) is an antifungal medication that fights certain infections caused by fungus. 4-[4-[4-[4-[[(3R,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one are its synonyms. With a Brand Names Noxafil, it has has the molecular formula C37H42F2N8O4 and molecular weight of 700.78. Posaconazole is a white powder and is insoluble in water.

Molecular Structure :

2. The uses of Posaconazole

Posaconazole ( Noxafil ) is used to prevent serious fungal infections in people with a weakened ability to fight infection. Posaconazol is also used to treat yeast infections of the mouth and throat including yeast infections that could not be treated successfully with other medications. Posaconazole is in a class of antifungals called triazoles. It works by slowing the growth of fungi that cause infection. HANGZHOU HOLYPHARM BIOTECH CO.,LTD, a professional supplier of active pharmaceutical ingredients and intermediates, agrochemicals and Veterinary products, said that Noxafil may also be used for other purposes not listed.

3. Mode of action of Posaconazole

Posaconazole ( Noxafil ) works by disrupting the close packing of acyl chains of phospholipids, impairing the functions of certain membrane-bound enzyme systems such as ATPase and enzymes of the electron transport system, thus inhibiting growth of the fungi. It does this by blocking the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase
and accumulation of methylated sterol precursors. Posaconazole is significantly more potent at inhibiting
14-alpha demethylase than itraconazole.

HANGZHOU HOLYPHARM BIOTECH CO.,LTD is a professional supplier of active pharmaceutical ingredients and intermediates; agrochemicals and Veterinary products. We are specialized in contract R&D and custom manufacturing. we have rich experience on a wide range of chemical reactions and fermentation from multi gram scale to hundred tons scale according to customers' requirement. Moreover, we are quite strong on registration. Our products have been registered in India, Vietnam, Latin America, Turkey, etc. HANGZHOU HOLYPHARM BIOTECH CO.,LTD is mainly engaged in the importing and exporting of pharmaceutical raw materials and intermediates to the markets of Europe and North America, and B2B e-commerce platform is undoubtedly an important platform for foreign trade enterprises who are looking for domestic opportunities. Holypharm forges their products to the foreign buyers' accustomed searching mode, which is the most effective way to advertise. We have three departments, PHARM DEPT. ,VETERINARY DEPT., AGROCHMICAL DEPT. We gather most qualified staffs with years of practical experience and knowledge in each department . They have better ideas on quality control, registration data, excellent packaging & labeling and logistics. To provide clients with more technology support, we will present efficient regulatory documents to show professional abilities in this field. Professional services The enterprise armed with knowledge will always keep its vitality and development. The human resources department in HANGZHOU HOLYPHARM will train its staff at regular intervals, to help them have a in-depth understanding of business regulations, foreign trade processes, chemical knowledge, communication skills, and so on. After foreign buyers gives the order, the company will give the one-stop services with factory-auditing, inspection, order management, export declaration to freight logistics. In addition, HANGZHOU HOLYPHARM will provide free extra services for foreign buyers like investigation of domestic market and consulting services, which is highly appraised by customers. As a company in the field of chemical export industry for many years, HOLYPHARM is engaged in improving the professional competence of the business staff and their professional services, which is not only the best way to win customers, but also helps to dig out the potential value of the chemical industry chain which are negligent.