Molecular Structure of (+)-Ephedrine (CAS NO.321-98-2):
Molecular Formula: C10H15NO
Molecular Weight: 165.2322
IUPAC Name: (1S,2R)-2-(Methylamino)-1-phenylpropan-1-ol
Synonyms of (+)-Ephedrine (CAS NO.321-98-2): (+)-Ephedrin ; (+)-Ephedrine anhydrous ; (1S,2R)-Ephedrine ; BRN 4231286 ; EINECS 206-293-3 ; L-(+)-Ephedrine ; alpha-(1-(Methylaminoethyl)benzenemethanol, (S-(R*,S*)- ; d-Ephedrine ; 2-Methylamino-1-phenylpropan-1-ol ; Benzenemethanol, alpha-((1R)-1-(methylamino)ethyl)-, (alphaS)- ; Benzenemethanol, alpha-(1-(methylamino)ethyl)-, (S-(R*,S*))-(9CI) ; Ephedrine, (+)-
CAS NO: 321-98-2
Classification Code: Drug / Therapeutic Agent Index of Refraction: 1.576
Surface Tension: 44 dyne/cm
Density: 1.33 g/cm3
Flash Point: 223.6 °C
Enthalpy of Vaporization: 70.43 kJ/mol
Boiling Point: 446.2 °C at 760 mmHg
Vapour Pressure: 3.73E-08 mmHg at 25°C
(+)-Ephedrine (CAS NO.321-98-2) is a sympathomimetic amine commonly used as a stimulant, appetite suppressant, concentration aid, decongestant, and to treat hypotension associated with anaesthesia.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 255mg/kg (255mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmaceutical Sciences. Vol. 53, Pg. 987, 1964. |
mouse | LD50 | intravenous | 105mg/kg (105mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Journal of Pharmacology and Experimental Therapeutics. Vol. 148, Pg. 158, 1965. |
Reported in EPA TSCA Inventory.
Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NOx.
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