(2S,4R)-4-Hydroxy-1-[(4-methylphenyl)sulfonyl]pyrrolidine-2-methanol supplier

Name
(3R,5S)-5-(hydroxymethyl)-1-tosylpyrrolidin-3-ol
EINECS
CAS No. 5605-46-9
Article Data10
CAS DataBase
Density 1.364
Solubility
Melting Point 132-133 ℃
Formula C₁₂H₁₇NO₄S
Boiling Point
Molecular Weight 271.337
Flash Point
Transport Information
Appearance
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms N-Tosylhydroxy-L-prolinol;
PSA 86.22000
LogP 1.12990

(2S,4R)-4-Hydroxy-1-[(4-methylphenyl)sulfonyl]pyrrolidine-2-methanol Specification

The (3R,5S)-5-(Hydroxymethyl)-1-tosylpyrrolidin-3-ol, with the CAS registry number 5605-46-9, is also known as N-Tosylhydroxy-L-prolinol. This chemical's molecular formula is C₁₂H₁₇NO₄S and molecular weight is 271.33.

Preparation: this chemical can be prepared by trans-4-hydroxy-1-(toluene-4-sulfonyl)-L-proline by heating. This reaction will need reagent BH₃ and solvent tetrahydrofuran with the reaction time of 10 hours. The yield is about 88%.

(3R,5S)-5-(Hydroxymethyl)-1-tosylpyrrolidin-3-ol can be prepared by trans-4-hydroxy-1-(toluene-4-sulfonyl)-L-proline by heating

Uses of (3R,5S)-5-(Hydroxymethyl)-1-tosylpyrrolidin-3-ol: it can be used to produce toluene-4-sulfonic acid 4-hydroxy-1-(toluene-4-sulfonyl)-pyrrolidin-2-ylmethyl ester at the temperature of -20 °C. It will need reagent pyridine with the reaction time of 2 hours. The yield is about 90%.

(3R,5S)-5-(Hydroxymethyl)-1-tosylpyrrolidin-3-ol can be used to produce toluene-4-sulfonic acid 4-hydroxy-1-(toluene-4-sulfonyl)-pyrrolidin-2-ylmethyl ester at the temperature of -20 °C

Product Name

(3R,5S)-5-(hydroxymethyl)-1-tosylpyrrolidin-3-ol

(2S,4R)-4-Hydroxy-1-[(4-methylphenyl)sulfonyl]pyrrolidine-2-methanol Specification

Related Products

Hot Products