• Name

  1-(4'-Sulfophenyl)-3-carboxy-5-pyrazolone

• EINECS 204-254-5
• CAS No. 118-47-8
• Density 1.75 g/cm³
• Solubility 272.6mg/L
• Melting Point 260-270
• Formula C₁₀H₈N₂O₆S
• Boiling Point 536.5℃[at 101 325 Pa]
• Molecular Weight 284.249
• Flash Point
• Transport Information
• Appearance
• Safety
• Risk Codes
• Molecular Structure
• Hazard Symbols Xi
• Synonyms 2-Pyrazoline-3-carboxylicacid, 5-oxo-1-(p-sulfophenyl)- (6CI,7CI,8CI);1-(4-Sulfophenyl)-3-carboxy-5-pyrazolone;1-(4-Sulfophenyl)-5-pyrazolone-3-carboxylic acid;1-(4'-Sulfophenyl)-3-carboxy-5-pyrazolone;1-(4'-Sulfophenyl)-3-carboxypyrazolone-5;1-(4'-Sulfophenyl)pyrazol-5-one-3-carboxylic acid;1-(p-Sulfophenyl)-5-pyrazolone-3-carboxylic acid;1-Phenyl-4'-sulfo-5-pyrazolone-3-carboxylic acid;3-Carboxy-1-(4-sulfophenyl)-5-pyrazolone;3-Carboxy-1-(p-sulfophenyl)-5-pyrazolone;5-Oxo-1-(p-sulfophenyl)-2-pyrazoline-3-carboxylic acid;NSC 50665;NSC 51118;PyT;Pyrazolone T;
• PSA 132.72000
• LogP 0.69200

Synthetic route

117-61-3

4,4'-diamino-2,2'-biphenyldisulfonic acid

118-47-8

5-oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid

C32H16N8O18S4(6-)*6Na(1+)

Conditions

Conditions	Yield
Stage #1: 4,4'-diamino-2,2'-biphenyldisulfonic acid With hydrogenchloride; sodium nitrite In water at 5℃; for 0.583333h; Stage #2: 5-oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid With sodium acetate In ethyl acetate; N,N-dimethyl-formamide at 5℃; for 1h;	70%

32432-55-6

3,5-diamino-2,4,6-trimethylbenzene-1-sulfonic acid

118-47-8

5-oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid

C29H19N8O15S3(5-)*5Na(1+)

Conditions

Conditions	Yield
Stage #1: 3,5-diamino-2,4,6-trimethylbenzene-1-sulfonic acid With hydrogenchloride; sodium nitrite In water at 5℃; for 0.583333h; Stage #2: 5-oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid With sodium acetate In ethyl acetate; N,N-dimethyl-formamide at 5℃; for 1h;	69%

697756-74-4

C26H25N5O15S3

118-47-8

5-oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid

C36H30N8O21S4

Conditions

Conditions	Yield
Stage #1: C26H25N5O15S3 With hydrogenchloride; aminosulfonic acid; sodium nitrite In water at 0 - 10℃; for 1h; pH=9; Stage #2: 5-oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid In water at 0 - 10℃; pH=7;	68.8%

118-47-8

5-oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid

4-[(5-hydroxy-7-sulfo-2-naphthyl)diazenyl]-5-oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid lithium and sodium salt

Conditions

Conditions	Yield
Stage #1: 7-amino-4-hydroxy-2-naphthalenesulfonic acid With lithium hydroxide; sodium nitrate In water pH=7 - 8; Stage #2: With hydrogenchloride In water at 0 - 10℃; for 1h; pH=1; Stage #3: 5-oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid With pyridine; lithium hydroxide In water at 0 - 10℃; for 0.333333h; pH=5;

1375454-29-7

C24H20N6O12S4

118-47-8

5-oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid

C44H30N12O24S6

Conditions

Conditions	Yield
Stage #1: C24H20N6O12S4 With hydrogenchloride; sodium nitrite In water at 5 - 15℃; for 2.08333h; Stage #2: 5-oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid With sodium carbonate In water at 15 - 20℃; for 2.41667h; pH=6.5 - 8.8; Stage #3: With potassium chloride; sodium chloride In water for 0.5h;

1-(4'-Sulfophenyl)-3-carboxy-5-pyrazolone Chemical Properties

1-(4'-Sulfophenyl)-3-carboxy-5-pyrazolone Toxicity Data With Reference