1-Propanaminium,3-carboxy-N,N,N-trimethyl-2-[[(tetradecylamino)carbonyl]amino]-, inner salt,(2R)- supplier

Name
3-(tetradecylcarbamoylamino)-4-trimethylammonio-butanoate
EINECS
CAS No. 250694-07-6
Article Data2
CAS DataBase
Density g/cm³
Solubility
Melting Point
Formula C22H45 N3 O3
Boiling Point °Cat760mmHg
Molecular Weight 399.618
Flash Point °C
Transport Information
Appearance white crystalline powder
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms (R)-4-Trimethylammonio-3-[(tetradecylcarbamoyl)amino]butyrate;ST 1326;Teglicar;
PSA 81.26000
LogP 3.98330

Synthetic route

: 4877-14-9
tetradecyl isocyanate

: 98063-21-9
(R)-3-(amino)-4-(trimethylammonio)butanoate

: 250694-07-6
teglicar

Conditions

Conditions	Yield
tetrabutyl-ammonium chloride In methanol at 5 - 20℃;	90%
In dimethyl sulfoxide at 40℃; for 60h;	57%

: 4897-84-1
Methyl 4-bromobutyrate

: 250694-07-6
teglicar

: (R)-4-trimethylammonium-3-(tetradecylcarbamoylamino)-butyrate of 3-(methoxycarbonyl)-propyl bromide

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 50℃;	87%

: 67-56-1
methanol

: 250694-07-6
teglicar

: methyl (R)-4-trimethylammonium-3-(tetradecylcarbamoyl)-amino-butyrate chloride

Conditions

Conditions	Yield
With thionyl chloride at 0 - 40℃; for 72h;	12%

: 250694-07-6
teglicar

: (R)-4-trimethylammonium-3-(tetradecylcarbamoyl)amino-butyrate hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In water

1-Propanaminium,3-carboxy-N,N,N-trimethyl-2-[[(tetradecylamino)carbonyl]amino]-, inner salt,(2R)- Specification

Teglicar, in vitro and in animal models, reduces gluconeogenesis and improves glucose homeostasis, refreshing the interest in selective and reversible L-CPT1 inhibition as a potential antihyperglycemic approach.For the detailed information of Teglicar, the solubility of Teglicar in water, the solubility of Teglicar in DMSO, the solubility of Teglicar in PBS buffer, the animal experiment (test) of Teglicar, the cell expriment (test) of Teglicar, the in vivo, in vitro and clinical trial test of Teglicar, the EC50, IC50,and Affinity of Teglicar, Please contact DC Chemicals.

Product Name

3-(tetradecylcarbamoylamino)-4-trimethylammonio-butanoate

Synthetic route

1-Propanaminium,3-carboxy-N,N,N-trimethyl-2-[[(tetradecylamino)carbonyl]amino]-, inner salt,(2R)- Specification

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