2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol

1.Introduction of 2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol

2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol ,with is CAS NO.6976-37-0, is a kind of White crystalline powder. It has synonyms of  Bis-Tris ; Bistris ; 2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol ; 2-(Bis(2-hydroxyethyl)amino))-2-hydroxymethyl-1,3-propanediol and 1,3-Propanediol, 2-(bis(2-hydroxyethyl)amino)-2-(hydroxymethyl)-. 2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol should be stored in shady and cool warehouse and mainly used as biochemical reagents and API intermediate.

2.Properties of 2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol

(1) Water Solubility: 1 M at 20 °C, clear, colorless (2) Sensitive: air sensitive (3) Index of Refraction: 1.562(4) Molar Refractivity: 50.47 cm3 (5) Molar Volume: 155.4 cm3 (6) Surface Tension: 73.3 dyne/cm  (7) Enthalpy of Vaporization: 83.94 kJ/mol (8) Vapour Pressure: 1.19E-10 mmHg at 25 °C
(9) XLogP3-AA: -3.3  (10) H-Bond Donor: 5 (11) H-Bond Acceptor: 6 (12) Rotatable Bond Count: 8 (13) Exact Mass: 209.126323
(14) MonoIsotopic Mass: 209.126323 (15) Topological Polar Surface Area: 104 (16) Heavy Atom Count: 14

3.Structure descriptors of 2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol

SMILES: C(CO)N(CCO)C(CO)(CO)CO
InChI: InChI=1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2
InChIKey: OWMVSZAMULFTJU-UHFFFAOYSA-N

4.Safety information of

Hazard Codes: Xi, Xn
Risk Statements: 36/37/38-21/22-20/21/22
R36/37/38:Irritating to eyes, respiratory system and skin.
R21/22:Harmful in contact with skin and if swallowed.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-36-36/37/39-22
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S22:Do not breathe dust.
WGK Germany: 3
F: 10-23
HS Code: 29221980