• Name

  2,2-Dimorpholinodiethylether

• EINECS 229-194-7
• CAS No. 6425-39-4
• Density 1.061 g/cm³
• Solubility 100g/L at 20℃
• Melting Point -28 °C
• Formula C₁₂H₂₄N₂O₃
• Boiling Point 333.9 °C at 760 mmHg
• Molecular Weight 244.334
• Flash Point 96.7 °C
• Transport Information
• Appearance STRAW YELLOW
• Safety 26-36
• Risk Codes 36
• Molecular Structure
• Hazard Symbols Xi
• Synonyms Morpholine,4,4'-(oxydiethylene)di- (6CI,7CI,8CI);4,4'-(Oxydiethylene)bis[morpholine];4,4'-(Oxydiethylene)dimorpholine;Bis(morpholinoethyl) ether;Bis[2-(4-morpholino)ethyl] ether;Di(2-morpholinoethyl) ether;Dimorpholinodiethyl ether;NSC28749;U-CAT 660M;b,b'-Dimorpholinodiethyl ether;
• PSA 34.17000
• LogP -0.45680

Synthetic route

3240-94-6

N-(2-chlorethyl)morpholine

622-40-2

2-(morpholin-4-yl)ethanol

6425-39-4

2,2'-dimorpholinodiethyl ether

Conditions

Conditions	Yield
With sodium hydroxide; adogen 464 In tetrahydrofuran for 6h; Heating;	84%
With sodium

637-39-8

triethanolamine hydrochloride

A

110-91-8

morpholine

B

622-40-2

2-(morpholin-4-yl)ethanol

C

1723-94-0

1,2-dimorpholylethane

D

6425-39-4

2,2'-dimorpholinodiethyl ether

Conditions

Conditions	Yield
at 190 - 230℃;

...Expand

637-39-8

triethanolamine hydrochloride

6425-39-4

2,2'-dimorpholinodiethyl ether

Conditions

Conditions	Yield
at 200 - 230℃;

3240-94-6

N-(2-chlorethyl)morpholine

2109-66-2

4-(2-hydroxypropyl)morpholine

A

6425-39-4

2,2'-dimorpholinodiethyl ether

B

alpha-methyl-bis<2(4-morpholino)ethyl> ether

C

beta-methyl bis<2(4-morpholino)ethyl> ether

Conditions

Conditions	Yield
With sodium hydroxide; adogen 464 In tetrahydrofuran for 6h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

...Expand

622-40-2

2-(morpholin-4-yl)ethanol

6425-39-4

2,2'-dimorpholinodiethyl ether

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: SOCl2 / 2 h / Heating 2: 50percent NaOH / Adogen 464 / tetrahydrofuran / 6 h / Heating View Scheme
Multi-step reaction with 2 steps 1: SOCl2 / 2 h / Heating 2: 84 percent / 50percent NaOH / Adogen 464 / tetrahydrofuran / 6 h / Heating View Scheme
With sulfuric acid at 130 - 200℃; for 15h;

7664-41-7

ammonia

111-46-6

diethylene glycol

6425-39-4

2,2'-dimorpholinodiethyl ether

Conditions

Conditions	Yield
With hydrogen; γ-Al2O3 (45 weight %), CuO (55 weight %), hydrogenated at 210℃; under 12001.2 Torr; Product distribution / selectivity;

102-71-6

triethanolamine

6425-39-4

2,2'-dimorpholinodiethyl ether

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sulfuric acid / 15 h / 130 - 200 °C 2: sulfuric acid / 15 h / 130 - 200 °C View Scheme

102-71-6

triethanolamine

A

622-40-2

2-(morpholin-4-yl)ethanol

B

6425-39-4

2,2'-dimorpholinodiethyl ether

Conditions

Conditions	Yield
With sulfuric acid at 130 - 200℃; for 15h; Temperature; Time;

6425-39-4

2,2'-dimorpholinodiethyl ether

148315-27-9

pentafluorophenyl ester of quinaldic acid

78224-46-1

morpholino(quinolin-2-yl)methanone

Conditions

Conditions	Yield
With palladium diacetate In chlorobenzene at 115℃; for 24h;	69%

6425-39-4

2,2'-dimorpholinodiethyl ether

108709-76-8

C12F24N2O3

Conditions

Conditions	Yield
With hydrogen fluoride In water at 50℃; under 1551.4 Torr; for 233h; average voltage of electrochemical cell = 5.8 volts; 20 amps;	44%

2,2-Dimorpholinodiethylether Chemical Properties

2,2-Dimorpholinodiethylether Uses

2,2-Dimorpholinodiethylether Safety Profile

2,2-Dimorpholinodiethylether Specification