• Name

  2,3-PYRAZINEDIAMINE

• EINECS
• CAS No. 13134-31-1
• Article Data9
• CAS DataBase
• Density 1.368 g/cm³
• Solubility
• Melting Point 205.6 °C
• Formula C₄H₆N₄
• Boiling Point 351.6 °C at 760 mmHg
• Molecular Weight 110.118
• Flash Point 193.5 °C
• Transport Information
• Appearance
• Safety
• Risk Codes
• Molecular Structure
• Hazard Symbols
• Synonyms Pyrazine,2,3-diamino- (7CI,8CI);2,3-Pyrazinediamine;NSC 139902;
• PSA 77.82000
• LogP 0.80340

Synthetic route

156331-25-8

2-amino-3-azidopyrazine

13134-31-1

pyrazine-2,3-diamine

Conditions

Conditions	Yield
With hydrogenchloride; tin(ll) chloride In methanol at 60℃; for 2h;	87%
With hydrogenchloride; tin(ll) chloride In methanol at 60℃;	70%

51097-07-5

[1,2,5]thiadiazolo[3,4-b]pyrazine

13134-31-1

pyrazine-2,3-diamine

Conditions

Conditions	Yield
With hydrogenchloride; tin(ll) chloride for 1h; Ambient temperature;	83%

6863-73-6

3-chloropyrazin-2-amine

13134-31-1

pyrazine-2,3-diamine

Conditions

Conditions	Yield
With ammonia In water at 130℃; Sealed tube;	11%
With ammonia; water; copper

21943-12-4

3-bromo-pyrazine-2-amine

13134-31-1

pyrazine-2,3-diamine

Conditions

Conditions	Yield
With ammonia; copper In ethanol at 140℃; for 20h;	2.05 g

89123-58-0

2,3-diamino-5-bromopyrazine

13134-31-1

pyrazine-2,3-diamine

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen In ethanol under 2068.65 Torr; for 8h;

13134-31-1

pyrazine-2,3-diamine

64817-81-8

2,3-dihydroxyanthracene

1356380-51-2

5,14-dihydro-1,4,5,14-tetraazapentacene

Conditions

Conditions	Yield
at 205 - 215℃; for 3h; Inert atmosphere;	98%

13134-31-1

pyrazine-2,3-diamine

530-62-1

1,1'-carbonyldiimidazole

16328-63-5

1H-imidazo<4,5-b>pyrazin-2(3H)-one

Conditions

Conditions	Yield
In tetrahydrofuran at 80℃; for 4h; Inert atmosphere;	92%

13134-31-1

pyrazine-2,3-diamine

12354-84-6, 12354-85-7

bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]

6487-48-5

potassium oxalate monohydrate

C34H49Cl4Ir3N4

Conditions

Conditions	Yield
In methanol at 20℃; for 3h;	85%

...Expand

13134-31-1

pyrazine-2,3-diamine

C22H15NO2

C26H17N5

Conditions

Conditions	Yield
With acetic acid Reflux;	82%

13134-31-1

pyrazine-2,3-diamine

57-13-6

urea

16328-63-5

1H-Imidazo<4,5-b>pyrazin-2-ol

Conditions

Conditions	Yield
In diphenylether at 240℃; for 5h;	57%

13134-31-1

pyrazine-2,3-diamine

931-17-9

1,2-Cyclohexanediol

1,2,3,4,6,7,8,9-octahydropyrazino[2,3-b]quinoxaline

Conditions

Conditions	Yield
With dodecacarbonyl-triangulo-triruthenium; potassium tert-butylate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In tert-Amyl alcohol at 130℃; for 10h; Inert atmosphere; Schlenk technique; Sealed tube;	56%

13134-31-1

pyrazine-2,3-diamine

76-05-1

trifluoroacetic acid

58885-00-0

2-(trifluoromethyl)-1H-imidazo[4.5-b]pyrazine

Conditions

Conditions	Yield
at 120℃; for 16h;	54%

13134-31-1

pyrazine-2,3-diamine

72856-73-6

2-methoxy-4-(methylsulfanyl)benzoic acid

99454-75-8

2-(2-methoxy-4-methylthiophenyl)-1H-imidazo<4,5-b>pyrazine

Conditions

Conditions	Yield
With trichlorophosphate for 4h; Heating;	45%

13134-31-1

pyrazine-2,3-diamine

492-70-6, 655-48-1, 2325-10-2, 38270-73-4, 52340-78-0, 579-43-1

1,2-diphenyl-1,2-ethanediol

6,7-diphenyl-1,2,3,4-tetrahydropyrazino[2,3-b]pyrazine

Conditions

Conditions	Yield
With dodecacarbonyl-triangulo-triruthenium; potassium tert-butylate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In tert-Amyl alcohol at 130℃; for 10h; Inert atmosphere; Schlenk technique; Sealed tube;	43%

13134-31-1

pyrazine-2,3-diamine

94-02-0

ethyl 3-oxo-3-phenylpropionate

ethyl 3-phenylpyrazino[2,3-b]pyrazine-2-carboxylate

Conditions

Conditions	Yield
Stage #1: ethyl 3-oxo-3-phenylpropionate With copper nitrate hemi(pentahydrate) In acetonitrile at 50℃; for 1h; Stage #2: pyrazine-2,3-diamine In methanol; acetonitrile at 20℃; for 2h;	33%

13134-31-1

pyrazine-2,3-diamine

2-(cyclopropanecarbonylamino)-3-(cyclopropylmethylcarbamoyl)-4,5,6,7-tetrahydrobenzothiophene-5-carboxylic acid

2-(cyclopropanecarbonylamino)-N-(cyclopropylmethyl)-5-(1H-imidazo[4,5-b]pyrazin-2-yl)-4,5,6,7-tetrahydrobenzothiophene-3-carboxamide

Conditions

Conditions	Yield
With pyridine; triphenylphosphine at 220℃; for 1h; Microwave irradiation;	26%

13134-31-1

pyrazine-2,3-diamine

1356380-54-5

9,10-bis((triisopropylsilyl)ethynyl)anthracene-2,3-diol

1356380-52-3

7,12-bis((triisopropylsilyl)ethynyl)-5,14-dihydro-1,4,5,14-tetraazapentacene

Conditions

Conditions	Yield
at 205 - 215℃; for 0.5h; Inert atmosphere;	25%

13134-31-1

pyrazine-2,3-diamine

3125-66-4

3-carbomethoxyphenyl isothiocyanate

methyl 3-(1H-imidazo[4,5-b]pyrazin-2-ylamino)benzoate

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 100℃; for 2h;	5%

13134-31-1

pyrazine-2,3-diamine

30989-75-4

ethoxy-1 formyl-2 butene-1

120757-21-3

5,14-dihydro-7,16-diethyldipyrazo<1,4,8,11>tetraazacyclotetradecine

Conditions

Conditions	Yield
In N,N-dimethyl-formamide for 4h; Heating;	3%

13134-31-1

pyrazine-2,3-diamine

79-14-1

glycolic Acid

55635-81-9

(1H-imidazo[4,5-b]pyrazin-2-yl)-methanol

Conditions

Conditions	Yield
at 140 - 150℃;

2,3-Diaminopyrazine Chemical Properties

2,3-Diaminopyrazine Specification