2,3-Diphenylthiazolidin-4-one

The 4-Thiazolidinone,2,3-diphenyl- with CAS registry number of 29291-15-4 is also known as 2,3-Diphenyl-4-thiazolidone. The IUPAC name is 2,3-Diphenyl-1,3-thiazolidin-4-one. In addition, the formula is C₁₅H₁₃NOS and the molecular weight is 255.33.

Physical properties about 4-Thiazolidinone,2,3-diphenyl- are: (1)ACD/LogP: 3.34; (2)ACD/LogD (pH 5.5): 3.34; (3)ACD/LogD (pH 7.4): 3.34; (4)ACD/BCF (pH 5.5): 203.45; (5)ACD/BCF (pH 7.4): 203.45; (6)ACD/KOC (pH 5.5): 1563.17; (7)ACD/KOC (pH 7.4): 1563.17; (8)#H bond acceptors: 2; (9)#Freely Rotating Bonds: 2; (10)Index of Refraction: 1.651; (11)Molar Refractivity: 74.58 cm³; (12)Molar Volume: 204.1 cm³; (13)Surface Tension: 52.7 dyne/cm; (14)Density: 1.25 g/cm³; (15)Flash Point: 259.2 °C; (16)Enthalpy of Vaporization: 77.45 kJ/mol; (17)Boiling Point: 504.9 °C at 760 mmHg; (18)Vapour Pressure: 2.55E-10 mmHg at 25 °C.

Preparation of 4-Thiazolidinone,2,3-diphenyl-: it is prepared by reaction of N-benzylidene-aniline with mercaptoacetic acid. The reaction needs reagent piperidine and solvent ethanol with other condition of heating for 2 hours. The yield is about 65%.

Uses of 4-Thiazolidinone,2,3-diphenyl-: it is used to produce 5-benzylidene-2,3-diphenyl-thiazolidin-4-one by reaction with benzaldehyde. The reaction occurs with reagent sodium ethoxide and solvent ethanol with other condition of heating for 20 minutes. The yield is about 70%.

You can still convert the following datas into molecular structure:
1. SMILES: O=C2N(c1ccccc1)C(SC2)c3ccccc3
2. InChI: InChI=1/C15H13NOS/c17-14-11-18-15(12-7-3-1-4-8-12)16(14)13-9-5-2-6-10-13/h1-10,15H,11H2
3. InChIKey: DQIBOSWPDZUOKX-UHFFFAOYAX
4. Std. InChI: InChI=1S/C15H13NOS/c17-14-11-18-15(12-7-3-1-4-8-12)16(14)13-9-5-2-6-10-13/h1-10,15H,11H2
5. Std. InChIKey: DQIBOSWPDZUOKX-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	178mg/kg (178mg/kg)		U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00574,