2,4-DIAMINOQUINAZOLINE

This chemical is called 2,4-Diaminoquinazoline, and its IUPAC name is quinazoline-2,4-diamine. With the molecular formula of C₈H₈N₄ , its molecular weight is 160.18. The CAS registry number of this chemical is 1899-48-5, and it is solid.

Other characteristics of the 2,4-Diaminoquinazoline can be summarised as followings: (1)ACD/LogP: 0.96; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -1.35; (4)ACD/LogD (pH 7.4): 0.06; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 10.02; (9)#H bond acceptors: 4; (10)#H bond donors: 4; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 32.26 Å²; (13)Index of Refraction: 1.795; (14)Molar Refractivity: 48.75 cm³; (15)Molar Volume: 114.5 cm³; (16)Polarizability: 19.32×10^-24cm³; (17)Surface Tension: 88.2 dyne/cm; (18)Density: 1.398 g/cm³; (19)Flash Point: 263.5 °C; (20)Enthalpy of Vaporization: 72.18 kJ/mol; (21)Boiling Point: 461 °C at 760 mmHg; (22)Vapour Pressure: 1.11E-08 mmHg at 25°C.

Production method of this chemical: The 2,4-Diaminoquinazoline could be obtained the reactants of cyanoguanidine and 2-amino-benzonitrile. This reaction needs the reagent of hydrochloric acid. The yield is 46 %. In addition, this reaction should be taken for 2 hours. The other condition is heating.

Uses of this chemical: The 4-hydrazino-quinazolin-2-ylamine could be obtained by the reactant of 2,4-Diaminoquinazoline. This reaction needs the reagent of N₂H₄*H₂O. The yield is 40 %. This reaction should be taken for 1.5 hours. The other condition is heating.

When you are using this chemical, please be cautious about it as the following: This chemical is irritating to eyes, respiratory system and skin, so you should wear suitable protective clothing when you use it. In case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
1.SMILES: n2c1c(cccc1)c(nc2N)N
2.InChI: InChI=1/C8H8N4/c9-7-5-3-1-2-4-6(5)11-8(10)12-7/h1-4H,(H4,9,10,11,12)
3.InChIKey: XELRMPRLCPFTBH-UHFFFAOYAG