2,4-Dimethyl-3-ethylpyrrole supplier

Name
2,4-Dimethyl-3-ethyl-1H-pyrrole
EINECS 208-234-7
CAS No. 517-22-6
Article Data39
CAS DataBase
Density 0.925 g/cm³
Solubility
Melting Point 63.75°C (estimate)
Formula C₈H₁₃N
Boiling Point 199.1 °C at 760 mmHg
Molecular Weight 123.198
Flash Point 71.7 °C
Transport Information
Appearance clear yellow to red-brown liquid
Safety 26-36-37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Pyrrole,3-ethyl-2,4-dimethyl- (6CI,7CI,8CI);2,4-Dimethyl-3-ethylpyrrole;3-Ethyl-2,4-dimethyl-1H-pyrrole;3-Ethyl-2,4-dimethylpyrrole;Cryptopyrrole;Kryptopyrrol;Kryptopyrrole;NSC 62025;
PSA 15.79000
LogP 2.19390

Synthetic route

: 2199-47-5
ethyl 3,5-dimethyl-4-ethylpyrrole-2-carboxylate

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

Conditions

Conditions	Yield
With sodium hydroxide In ethylene glycol for 1h; Heating;	100%
With potassium hydroxide In ethylene glycol for 5h; Heating;	80%
With ethylene glycol; potassium hydroxide; hydrazinium sulfate In tetrahydrofuran for 2h; Reflux;	76%
With sodium hydroxide In methanol; water for 2h; Heating;	17%
With ethylene glycol; potassium hydroxide

: 2386-26-7
ethyl 4-acetyl-3,5-dimethylpyrrole-2-carboxylate

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

Conditions

Conditions	Yield
With potassium hydroxide; hydrazine hydrate In diethylene glycol for 3h; Heating;	82%
With potassium hydroxide; hydrazine hydrate In diethylene glycol Heating;	75%
With sodium ethanolate; hydrazine hydrate at 165 - 170℃; im Autoklaven;

: 2386-25-6
2,4-dimethyl-3-acetylpyrrole

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

Conditions

Conditions	Yield
With lithium aluminium tetrahydride	81%
With lithium aluminium tetrahydride In tetrahydrofuran for 4.5h; Heating;	75%
With lithium aluminium tetrahydride In tetrahydrofuran at 85℃; for 4h;	60%

: 1500-91-0
4-ethyl-3,5-dimethylpyrrole-2-carbaldehyde

A: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

B: 542-59-6
2-hydroxyethyl acetate

Conditions

Conditions	Yield
With ethylene glycol; toluene-4-sulfonic acid In benzene for 0.25h; Heating;	A 35% B n/a

: 1-(2,4-dimethyl-pyrrol-3-yl)-ethanone-hydrazone

: 141-52-6
sodium ethanolate

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

Conditions

Conditions	Yield
at 150 - 160℃;

: hemin

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

Conditions

Conditions	Yield
With hydrogen iodide; acetic acid

: 2386-26-7
ethyl 4-acetyl-3,5-dimethylpyrrole-2-carboxylate

A: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

B: 3-ethyl-2,4-dimethyl-pyrrol-1-ylamine

Conditions

Conditions	Yield
With sodium ethanolate; hydrazine hydrate

: 1925-61-7
benzyl 4-ethyl-3,5-dimethylpyrrole-2-carboxylate

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

Conditions

Conditions	Yield
With methanol; nickel at 120℃; under 73550.8 Torr; Hydrogenation;

: 2-(4-ethyl-3,5-dimethyl-pyrrole-2-carbonyl)-benzoic acid

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

Conditions

Conditions	Yield
With hydrogen iodide; acetic acid

: 635-65-4
bilirubin

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

Conditions

Conditions	Yield
With hydrogen iodide; acetic acid

: 17106-07-9
4-ethyl-3,5-dimethyl-1H-pyrrole-2-carboxylic acid

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

Conditions

Conditions	Yield
at 100 - 102℃; under 20 - 22 Torr; Yield given;

: 2644-60-2
γ-phylloporphyrin-XV

A: 600-28-2
2,3-dimethyl-1H-pyrrole

B: 625-82-1
2,4-dimethyl-1H-pyrrole

C: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

D: 491-18-9
4-ethyl-2,3-dimethyl-1H-pyrrole

E: 53365-83-6
3-(4,5-dimethyl-pyrrol-3-yl)-propionic acid methyl ester

F: 54474-51-0
methyl 2,4-dimethyl-3-pyrrolepropionate

Conditions

Conditions	Yield
With hydrogen iodide Product distribution; structural analysis by degradative techniques;

...Expand

: 62222-14-4
meso-porphyrin-II-dimethyl ester

A: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

B: 491-18-9
4-ethyl-2,3-dimethyl-1H-pyrrole

C: 53365-83-6
3-(4,5-dimethyl-pyrrol-3-yl)-propionic acid methyl ester

D: 54474-51-0
methyl 2,4-dimethyl-3-pyrrolepropionate

Conditions

Conditions	Yield
With hydrogen iodide Product distribution; structural analysis by degradative techniques;

...Expand

: 26608-34-4
etioporphyrin III

A: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

B: 491-18-9
4-ethyl-2,3-dimethyl-1H-pyrrole

Conditions

Conditions	Yield
With hydrogen iodide Product distribution; structural analysis by degradative techniques;

: 448-71-5
ethioporphyrin I

A: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

B: 491-18-9
4-ethyl-2,3-dimethyl-1H-pyrrole

Conditions

Conditions	Yield
With hydrogen iodide Product distribution; structural analysis by degradative technique;

: 1263-63-4
mesoporphyrin IX DME

A: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

B: 491-18-9
4-ethyl-2,3-dimethyl-1H-pyrrole

C: 53365-83-6
3-(4,5-dimethyl-pyrrol-3-yl)-propionic acid methyl ester

D: 54474-51-0
methyl 2,4-dimethyl-3-pyrrolepropionate

Conditions

Conditions	Yield
With hydrogen iodide Product distribution; structural analysis by degradative techniques;

...Expand

3.5-dimethyl-4-vinyl-pyrrole-carboxylic acid-(2): 3.5-dimethyl-4-vinyl-pyrrole-carboxylic acid-(2)

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

Conditions

Conditions	Yield
With methanol; platinum Hydrogenation;

4-methyl-3-ethyl-pyrrol-aldehyde-(2): 4-methyl-3-ethyl-pyrrol-aldehyde-(2)

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

Conditions

Conditions	Yield
With sodium ethanolate; hydrazine hydrate at 160 - 165℃; unter Druck;

bilirubinic acid: bilirubinic acid

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

Conditions

Conditions	Yield
With hydrogen iodide; acetic acid

: 5-bromo-5'-bromomethyl-3,4'-diethyl-4,3'-dimethyl-1H,2'H-2,2'-methanylylidene-bis-pyrrole

: 10034-85-2
hydrogen iodide

: 64-19-7
acetic acid

A: 488-92-6
3-ethyl-4-methyl-1H-pyrrole

B: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

C: 520-69-4
3-ethyl-2,4,5-trimethyl-1H-pyrrole

...Expand

: 10034-85-2
hydrogen iodide

: 49619-17-2
(3-ethyl-5-bromo-4-methyl-pyrrol-2-yl)-(4-ethyl-3,5-dimethyl-pyrrol-2-ylidene)-methane; tribromoide

: 64-19-7
acetic acid

A: 488-92-6
3-ethyl-4-methyl-1H-pyrrole

B: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

C: 520-69-4
3-ethyl-2,4,5-trimethyl-1H-pyrrole

...Expand

: 1540-34-7
3-ethyl-2,4-pentanedione

selenacetylacetone: selenacetylacetone

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 60 percent / Zn, AcOH / 1 h / Heating 2: 80 percent / KOH / ethane-1,2-diol / 5 h / Heating View Scheme

: 1925-61-7
benzyl 4-ethyl-3,5-dimethylpyrrole-2-carboxylate

A: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

B <4-ethyl-5-formyl-3-methyl-pyrrol-2-yl>-carbamic acid ethyl ester: <4-ethyl-5-formyl-3-methyl-pyrrol-2-yl>-carbamic acid ethyl ester

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: H2, triethylamine / 10percent Pd/C / ethanol / 2 h 2: 100 - 102 °C / 20 - 22 Torr View Scheme

: 123-54-6
acetylacetone

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 1) NaNO2, AcOH 2) Zn dust, AcOH / 1) H2O, 25 deg C, overnight 2) reflux, 24 h 2: 82 percent / KOH, NH2NH2*H2O / bis-(2-hydroxy-ethyl) ether / 3 h / Heating View Scheme
Multi-step reaction with 3 steps 1: zinc; acetic acid 2: diborane 3: ethylene glycol; potassium hydroxide View Scheme
Multi-step reaction with 3 steps 1.1: sodium nitrite; acetic acid / water / 4 h / 20 °C / Cooling with ice 1.2: 1 h / 60 °C / Cooling with ice 2.1: potassium hydroxide / ethylene glycol / 4 h / 160 °C 3.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 85 °C View Scheme
Multi-step reaction with 3 steps 1.1: acetic acid; sodium nitrite / water / 12 h / 0 - 25 °C 1.2: 1 h / 60 °C / Cooling with ice 2.1: potassium hydroxide / 1,2-dimethoxyethane / 4 h / 160 °C 3.1: lithium aluminium tetrahydride / tetrahydrofuran / 5 h / Cooling with ice; Reflux View Scheme

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 18818-25-2
methyl 3-(5-formyl-2,4-dimethyl-1H-pyrrol-3-yl)propanoate

: (Z)-methyl 3-(5-((4-ethyl-3,5-dimethyl-2H-pyrrol-2-ylidene)methyl)-2,4-dimethyl-1H-pyrrol-3-yl)propanoate hydrobromide

Conditions

Conditions	Yield
With hydrogen bromide In tetrahydrofuran; methanol; water at 20℃; for 3h; Inert atmosphere;	99%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 1350764-68-9
C15H5BBr6F2N2

: C31H29BBr4F2N4

Conditions

Conditions	Yield
In toluene at 20℃; for 0.5h; Inert atmosphere;	98%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 2199-59-9
ethyl (5-formyl-2,4-dimethyl-1H-pyrrole)-3-carboxylate

: (Z)-ethyl 5-((4-ethyl-3,5-dimethyl-2H-pyrrol-2-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate hydrobromide

Conditions

Conditions	Yield
With hydrogen bromide In tetrahydrofuran; methanol at 20℃; Inert atmosphere;	98%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 2-((trifluoromethyl)thio)benzo[d]isothiazol-3(2H)-one 1,1-dioxide

: 3-ethyl-2,4-dimethyl-5-((trifluoromethyl)thio)-1H-pyrrole

Conditions

Conditions	Yield
With chloro-trimethyl-silane In dichloromethane at 20℃; for 0.5h; Schlenk technique;	97%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 2-((trifluoromethyl)thio)benzo[d]isothiazol-3(2H)-one 1,1-dioxide

: 2,4-dimethyl-3-ethyl-5-trifluoromethylpyrrole

Conditions

Conditions	Yield
With chloro-trimethyl-silane In dichloromethane at 20℃; for 0.5h; Green chemistry;	97%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 117506-45-3
2-(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)propanedinitrile

: 137123-51-4
2-(4-ethyl-3,5-dimethyl-1H-pyrrol-2-yl)-2-(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)malononitrile

Conditions

Conditions	Yield
In acetic acid for 2h; Ambient temperature;	95%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 1128076-99-2
C18H25NO2S

: 1128077-15-5
C18H33NS

Conditions

Conditions	Yield
With N,N-dimethyl acetamide; magnesium bromide at 90℃; for 1h;	95%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 14204-27-4
N-phenylthiophthalimide

: 1128077-07-5
3-ethyl-2,4-dimethyl-5-(phenylthio)-1H-pyrrole

Conditions

Conditions	Yield
With N,N-dimethyl acetamide; magnesium bromide at 90℃; for 1h;	95%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 88683-45-8
2-((4-methoxyphenyl)thio)isoindoline-1,3-dione

: 1128077-18-8
C15H19NOS

Conditions

Conditions	Yield
With N,N-dimethyl acetamide; magnesium bromide at 90℃; for 1h;	95%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 1227204-45-6
C22H23IN2O2

: 1227204-48-9
1-(5-((4-ethyl-3,5-dimethyl-1H-pyrrol-2-yl)(4-iodophenyl)methyl)-2,4-dimethyl-1H-pyrrol-3-yl)ethanone

Conditions

Conditions	Yield
With acetyl chloride In methanol at -78 - 0℃; Inert atmosphere;	95%
With methanol; acetyl chloride at -78 - 0℃; for 1.5h;	95%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 677-25-8
ethylenesulfonyl fluoride

: 2-(4-ethyl-3,5-dimethyl-1H-pyrrol-2-yl)ethane-1-sulfonyl fluoride

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 0.0833333h;	95%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 109-63-7
boron trifluoride diethyl etherate

: 5651-86-5
4-(prop-2-ynyloxy)benzaldehyde

: 4,4-difluoro-8-(prop-2-ynyloxy)benzene-1,3,5,7-tetramethyl-2,6-diethyl-4-bora-3a,4a-diaza-s-indacene

Conditions

Conditions	Yield
Stage #1: 2,4-dimethyl-3-ethyl-pyrrole; 4-(prop-2-ynyloxy)benzaldehyde With trifluoroacetic acid In dichloromethane at 20℃; Inert atmosphere; Stage #2: With 2,3-dicyano-5,6-dichloro-p-benzoquinone In dichloromethane at 0 - 20℃; for 0.333333h; Inert atmosphere; Stage #3: boron trifluoride diethyl etherate With triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere;	94%
Stage #1: 2,4-dimethyl-3-ethyl-pyrrole; 4-(prop-2-ynyloxy)benzaldehyde With trifluoroacetic acid In dichloromethane at 25℃; for 12h; Inert atmosphere; Stage #2: In dichloromethane at 25℃; Inert atmosphere; Stage #3: boron trifluoride diethyl etherate With triethylamine In dichloromethane at 25℃; for 12h; Inert atmosphere;	22%
Stage #1: 2,4-dimethyl-3-ethyl-pyrrole; 4-(prop-2-ynyloxy)benzaldehyde Stage #2: With 2,3-dicyano-5,6-dichloro-p-benzoquinone Stage #3: boron trifluoride diethyl etherate Alkaline conditions;

...Expand

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 87751-69-7
rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene

: (E)-4-ethyl-3,5-dimethyl-2-(1,3-diphenyl-2-propenyl)pyrrole

Conditions

Conditions	Yield
With bis(η3-allyl-μ-chloropalladium(II)); C34H23P; potassium carbonate In toluene; acetonitrile at -20℃; for 38h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	93%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 105235-04-9
1-methyl-5-pyrrol-2-ylpyrrole-2-carbaldehyde

: 105256-97-1, 105257-09-8
3-ethyl-2,4,12-trimethylprodigiosene hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In ethanol at 5℃; for 0.333333h;	92%

: 1-{5-[(benzyl-hydroxy-amino)-phenyl-methyl]-2,4-dimethyl-1H-pyrrol-3-yl}-ethanone

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 1-(5-((4-ethyl-3,5-dimethyl-1H-pyrrol-2-yl)(phenyl)methyl)-2,4-dimethyl-1H-pyrrol-3-yl)ethanone

Conditions

Conditions	Yield
With acetyl chloride In methanol at -78 - 0℃; Inert atmosphere;	92%
With methanol; acetyl chloride at -78 - 0℃; for 1.5h;	92%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 1290536-55-8
3,7-bis(N,N-dimethylamino)-5,5-dimethyldibenzo[b,e]silin-10(5H)-one

: C27H36N3Si(1+)

Conditions

Conditions	Yield
Stage #1: 3,7-bis(N,N-dimethylamino)-5,5-dimethyldibenzo[b,e]silin-10(5H)-one With trifluoromethylsulfonic anhydride In acetonitrile at 0℃; for 0.166667h; Inert atmosphere; Stage #2: 2,4-dimethyl-3-ethyl-pyrrole In acetonitrile at 0 - 25℃; for 0.166667h; Inert atmosphere;	90.1%
Stage #1: 3,7-bis(N,N-dimethylamino)-5,5-dimethyldibenzo[b,e]silin-10(5H)-one With trifluoromethylsulfonic anhydride Stage #2: 2,4-dimethyl-3-ethyl-pyrrole

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 17796-70-2
2-ethylthioisoindoline-1,3-dione

: 1128077-89-3
C10H17NS

Conditions

Conditions	Yield
With N,N-dimethyl acetamide; magnesium bromide at 90℃; for 1h;	90%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 1416276-96-4
bis(4-(methoxycarbonyl)phenyl)iodonium trifluoromethanesulfonate

: methyl 4-(4-ethyl-3,5-dimethyl-1H-pyrrol-2-yl)benzoate

Conditions

Conditions	Yield
With tris(bipyridine)ruthenium(II) dichloride hexahydrate In acetonitrile at 25℃; for 12h; Inert atmosphere; Irradiation; Schlenk technique;	90%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 2-((difluoromethyl)thio)isoindoline-1,3-dione

: 2-((difluoromethyl)thio)-4-ethyl-3,5-dimethyl-1H-pyrrole

Conditions

Conditions	Yield
With chloro-trimethyl-silane In 1,2-dichloro-ethane at 80 - 120℃; for 16h; Schlenk technique;	90%
With chloro-trimethyl-silane In dichloromethane at 80 - 120℃; Inert atmosphere; Sealed tube;	90%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 24424-99-5
di-tert-butyl dicarbonate

: tert-butyl 3-ethyl-2,4-dimethylpyrrole-1-carboxylate

Conditions

Conditions	Yield
With dmap In acetonitrile at 20℃; for 1h;	90%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 37059-18-0
benzyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate

: (Z)-benzyl 5-((4-ethyl-3,5-dimethyl-2H-pyrrol-2-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate hydrobromide

Conditions

Conditions	Yield
With hydrogen bromide In tetrahydrofuran; methanol at 20℃; Inert atmosphere;	90%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 14204-26-3
N-(benzylthio)phthalimide

: 1128077-10-0
C15H19NS

Conditions

Conditions	Yield
With N,N-dimethyl acetamide; magnesium bromide at 90℃; for 1h;	89%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 1391852-14-4
C15H13ClN2

: 1402649-93-7
C23H25N3

Conditions

Conditions	Yield
With trichlorophosphate In dichloromethane at 20℃; for 12h; Cooling with ice; Inert atmosphere;	89%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 13219-74-4
4-ethyl-3,5,N,N-tetramethylpyrrole-2-carboxamide

: 13228-22-3
bis(4-ethyl-3,5-dimethyl-pyrrol-2-yl)ketone

Conditions

Conditions	Yield
Stage #1: 4-ethyl-3,5,N,N-tetramethylpyrrole-2-carboxamide With trichlorophosphate at 50℃; for 0.25h; Stage #2: 2,4-dimethyl-3-ethyl-pyrrole In dichloromethane for 1.5h; Reflux; Stage #3: With sodium carbonate In dichloromethane; water for 2h; Reflux;	89%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 73930-97-9
3-acetoxy-1,3-diphenylpropene

: C23H25N

Conditions

Conditions	Yield
With bis(η3-allyl-μ-chloropalladium(II)); C37H40NO4PSi2; potassium carbonate; N-Trimethylsilylacetamide In dichloromethane at 23℃; for 2h; Inert atmosphere; Schlenk technique;	89%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 54764-96-4
3-methoxypyrrole-2-carboxaldehyde

A: 1233087-60-9
3,5-dimethyl-4-ethyl-2-(3-methoxypyrrolyl-2-methylene)-2H-pyrrole

B: 1233087-61-0
3,5-dimethyl-4-ethyl-2-(3-methoxypyrrolyl-2-methylene)-2H-pyrrolium dichlorophosphate

Conditions

Conditions	Yield
With trichlorophosphate In dichloromethane; pentane for 1.01667h; Cooling;	A n/a B 86%

...Expand

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 1414345-77-9
10-chloro-5,5-difluoro-5H-4λ4,5λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinine

: 1582309-41-8
C17H18BF2N3

Conditions

Conditions	Yield
In toluene at 20℃; for 0.05h; Inert atmosphere;	86%

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 109-63-7
boron trifluoride diethyl etherate

: (3,5-dimethyl-1H-pyrrol-2-yl)(p-tolyl)methanone

: 2-ethyl-4,4-difluoro-1,3,5,7-tetramethyl-8-(4-methylphenyl)-4-bora-3a,4a-diaza-s-indacene

Conditions

Conditions	Yield
Stage #1: 2,4-dimethyl-3-ethyl-pyrrole; boron trifluoride diethyl etherate; (3,5-dimethyl-1H-pyrrol-2-yl)-p-tolyl-methanone at 20℃; for 2h; Schlenk technique; Inert atmosphere; Stage #2: With N-ethyl-N,N-diisopropylamine at 20℃; for 4h; Schlenk technique; Inert atmosphere;	86%

...Expand

: 517-22-6
2,4-dimethyl-3-ethyl-pyrrole

: 16132-27-7
benzyl 5-N,N-dimethylamido-3,4-dimethylpyrrole-2-carboxylate

: 16132-42-6
benzyl 8-ethyl-2,3,7,9-tetramethyl-5-dipyrroketone-1-carboxylate

Conditions

Conditions	Yield
Stage #1: benzyl 5-N,N-dimethylamido-3,4-dimethylpyrrole-2-carboxylate With trichlorophosphate at 50℃; for 5h; Stage #2: 2,4-dimethyl-3-ethyl-pyrrole In dichloromethane at 30℃; Inert atmosphere; Stage #3: With water; sodium acetate In dichloromethane at 50℃; for 3h; Inert atmosphere;	85.7%

2,4-Dimethyl-3-ethylpyrrole Chemical Properties

Molecular Structure:Molecular Formula: C₈H₁₃N
Molecular Weight: 123.2
IUPAC Name: 3-Ethyl-2,4-dimethyl-1H-pyrrole
CAS No: 517-22-6
H bond acceptors: 1
H bond donors: 1
#Freely Rotating Bonds: 1
Polar Surface Area: 4.93 Å²
Index of Refraction: 1.511
Molar Refractivity: 39.88 cm³
Molar Volume: 133.1 cm³
Surface Tension: 32.8 dyne/cm
Density: 0.925 g/cm³
Flash Point: 71.7 °C
Enthalpy of Vaporization: 41.75 kJ/mol
Boiling Point: 199.1 °C at 760 mmHg
Vapour Pressure: 0.491 mmHg at 25°C
InChI: InChI=1/C8H13N/c1-4-8-6(2)5-9-7(8)3/h5,9H,4H2,1-3H3
InChIKey: ZEBBLOXDLGIMEG-UHFFFAOYAU
Std. InChI: InChI=1S/C8H13N/c1-4-8-6(2)5-9-7(8)3/h5,9H,4H2,1-3H3
Std. InChIKey: ZEBBLOXDLGIMEG-UHFFFAOYSA-N
Synonyms of 1H-Pyrrole,3-ethyl-2,4-dimethyl- (CAS No.517-22-6): Timtec-bb sbb004274 ; Kryptopyrrole ; Cryptopyrrole ; 'mauve factor' reagent ; 3-Ethyl-2,4-dimethylpyrrol ; 3-Ethyl-2,4-dimethylpyrrole ; 2,4-Dimethyl-3-ethyl-1H-pyrrole ; 2,4-Dimethyl-3-ethylpyrrole
Product Categories: Pharmaceutial intermediates

2,4-Dimethyl-3-ethylpyrrole Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	77mg/kg (77mg/kg)	BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Journal of Medicinal Chemistry. Vol. 11, Pg. 1251, 1968.

2,4-Dimethyl-3-ethylpyrrole Safety Profile

Hazard Codes: Irritant Xi
Risk Statements:36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements:26-36-37/39
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S37/39:Wear suitable gloves and eye/face protection.
WGK Germany:3
RTECS:UX9629500

Product Name

2,4-Dimethyl-3-ethyl-1H-pyrrole

Synthetic route

2,4-Dimethyl-3-ethylpyrrole Chemical Properties

2,4-Dimethyl-3-ethylpyrrole Toxicity Data With Reference

2,4-Dimethyl-3-ethylpyrrole Safety Profile

Related Products

Hot Products