2,5-Diaminotoluene

IUPAC Name: 2-Methylbenzene-1,4-diamine
Molecular Formula: C₇H₁₀N ₂
Molecular Weight: 122.17 g/mol
Canonical SMILES: c1(c(ccc(c1)N)N)C
InChI: InChI=1/C7H10N2/c1-5-4-6(8)2-3-7(5)9/h2-4H,8-9H2,1H3
EINECS: 202-442-1
Classification Code: Mutation data; Skin / Eye Irritant; Tumor data
Product Categories: Intermediates of Dyes and Pigments
Density: 1.107 g/cm³
Flash Point: 140.6 °C
Enthalpy of Vaporization: 51.2 kJ/mol
Boiling Point: 273.7 °C at 760 mmHg
Melting Point: 64 °C
Vapour Pressure of 2,5-Diaminotoluene (CAS NO.95-70-5): 0.00565 mmHg at 25 °C

 2,5-Diaminotoluene (CAS NO.95-70-5) can be used in the manufacture of dyes.

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 16 ,1978,p. 97.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Poison by ingestion and subcutaneous routes. A skin irritant. Mutation data reported. Questionable carcinogen. Has a toxic action upon the liver and can cause fatty degeneration of that organ. Its total effect upon the body seems to take place three different ways. It is toxic to the central nervous system, producing jaundice by action on the liver and spleen, and anemia by destruction of the red blood cells. This action is quite similar to that of aniline, although by no means identical with it. Its high boiling point and the fact that the material is solid at room temperature make it somewhat less hazardous than aniline, particularly at ordinary working temperatures. The literature contains a reference to a permanent injury to an eye due to the use of this material as an eyelash dye. It is considered to be an irritating dye material. When heated to decomposition it emits toxic fumes of NO_x. 
Hazard Codes: T,N
Risk Statements: 20/21-25-43-51/53 
R20/21: Harmful by inhalation and in contact with skin. 
R25: Toxic if swallowed. 
R43: May cause sensitization by skin contact. 
R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 24-37-45-61 
S24: Avoid contact with skin. 
S37: Wear suitable gloves. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
HazardClass: 6.1(b)
PackingGroup of 2,5-Diaminotoluene (CAS NO.95-70-5): III

 2,5-Diaminotoluene (CAS NO.95-70-5), its Synonyms are 2,5-Toluenediamine ; 2-Methyl-1,4-benzenediamine ; p-Toluenediamine ; 1,4-Benzenediamine, 2-methyl- ; 2-Methyl-p-phenylenediamine ; 2-Methyl-para-phenylenediamine ; 4-Amino-2-methylaniline ; Toluene-2,5-diamine .