2,7-Diaminofluorene

EPA Genetic Toxicology Program.

2,7-Diaminofluorene, with the CAS registry number 525-64-4, is also named as 2,7-Fluorenediamine. It belongs to the product categories of Fluorene Derivatives; Electronic Chemicals; Fluorenes; Fluorenes & Fluorenones. Its EINECS number is 208-377-5. This chemical's molecular formula is C₁₃H₁₂N₂ and molecular weight is 196.25. What's more, its systematic name is 2,7-Diaminofluorene. Its classification codes are: (1)Mutation data; (2)Tumor data. This chemical should be sealed and stored in a cool and dry place. Moreover, it should be protected from strong heat and fire. It is a kind of peroxidase reagent for blood smears. 

Physical properties of 2,7-Diaminofluorene are: (1)ACD/LogP: 1.984; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.93; (4)ACD/LogD (pH 7.4): 1.98; (5)ACD/BCF (pH 5.5): 16.71; (6)ACD/BCF (pH 7.4): 18.92; (7)ACD/KOC (pH 5.5): 252.00; (8)ACD/KOC (pH 7.4): 285.39; (9)#H bond acceptors: 2; (10)#H bond donors: 4; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 52.04 Å²; (13)Index of Refraction: 1.75; (14)Molar Refractivity: 62.268 cm³; (15)Molar Volume: 152.893 cm³; (16)Polarizability: 24.685×10^-24cm³; (17)Surface Tension: 67.6 dyne/cm; (18)Density: 1.284 g/cm³; (19)Flash Point: 283.628 °C; (20)Enthalpy of Vaporization: 72.892 kJ/mol; (21)Boiling Point: 467.021 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.

Preparation: this chemical can be prepared by 2,7-dinitro-fluorene at the temperature of 160 °C. This reaction will need reagent hydrazine and solvent acetone with the reaction time of 2 hours. The yield is about 62%.

Uses of 2,7-Diaminofluorene: it can be used to produce 2,7-bis(3',3',7'-trimethyloct-6'-enylideneamino)fluorene at the ambient temperature. It will need reagent 4 Angstroem powdered MC and solvent CH₂Cl₂. The yield is about 98%.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing.

You can still convert the following datas into molecular structure:
(1)SMILES: c1cc(cc3c1c2c(cc(N)cc2)C3)N
(2)Std. InChI: InChI=1S/C13H12N2/c14-10-1-3-12-8(6-10)5-9-7-11(15)2-4-13(9)12/h1-4,6-7H,5,14-15H2
(3)Std. InChIKey: SNCJAJRILVFXAE-UHFFFAOYSA-N