2-AMINO-4-METHOXY-3-NITROPYRIDINE

The 2-Pyridinamine,4-methoxy-3-nitro-, with the CAS registry number 84487-08-1, has the systematic name of 4-methoxy-3-nitropyridin-2-amine. It is a kind of yellow crystalline solid, and belongs to the following product categories: Nucleotides and Nucleosides; Bases & Related Reagents; Nucleotides; Pyridines. And the molecular formula of the chemical is C₆H₇N₃O₃.

The characteristics of 2-Pyridinamine,4-methoxy-3-nitro- are as followings: (1)ACD/LogP: 1.74; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.74; (4)ACD/LogD (pH 7.4): 1.74; (5)ACD/BCF (pH 5.5): 12.33; (6)ACD/BCF (pH 7.4): 12.43; (7)ACD/KOC (pH 5.5): 209.75; (8)ACD/KOC (pH 7.4): 211.32; (9)#H bond acceptors: 6; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 93.96 Å²; (13)Index of Refraction: 1.608; (14)Molar Refractivity: 41.8 cm³; (15)Molar Volume: 120.7 cm³; (16)Polarizability: 16.57×10^-24cm³; (17)Surface Tension: 62.3 dyne/cm; (18)Density: 1.4 g/cm³; (19)Flash Point: 169.6 °C; (20)Enthalpy of Vaporization: 60.21 kJ/mol; (21)Boiling Point: 356.8 °C at 760 mmHg; (22)Vapour Pressure: 2.85E-05 mmHg at 25°C. 

Preparation of 2-Pyridinamine,4-methoxy-3-nitro-: This chemical can be prepared by 4-chloro-3-nitro-pyridin-2-ylamine and methanol. The reaction will need reagent Na. The reaction time is 2 hours with heating, and the yield is about 56%. 

Uses of 2-Pyridinamine,4-methoxy-3-nitro-: It can react be used to produce 2,3-diamino-4-methoxypyridine. This reaction will need reagent H₂, catalyst 10% Pd/C, and the menstruum methanol. The reaction time is 1 hour with pressure of 760.0002Pa, and the yield is about 87%.   

Addtionally, the following datas could be converted into the molecular structure:
(1)SMILES: O=[N+]([O-])c1c(ccnc1N)OC
(2)InChI: InChI=1/C6H7N3O3/c1-12-4-2-3-8-6(7)5(4)9(10)11/h2-3H,1H3,(H2,7,8)
(3)InChIKey: PHZNRPWDIPHQNO-UHFFFAOYAV