Product Name

  • Name

    3-[2-[[(2-Methoxyphenyl)Methyl]aMino]ethyl]-2,4(1H,3 H)-quinazolinedione

  • EINECS
  • CAS No. 1028307-48-3
  • Density 1.232
  • Solubility
  • Melting Point
  • Formula C18H19N3O3
  • Boiling Point
  • Molecular Weight 325.36
  • Flash Point
  • Transport Information
  • Appearance
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 1028307-48-3 (3-[2-[[(2-Methoxyphenyl)Methyl]aMino]ethyl]-2,4(1H,3 H)-quinazolinedione)
  • Hazard Symbols
  • Synonyms 3-{2-[(2-Methoxybenzyl)amino]ethyl}-2,4(1H,3H)-quinazolinedione; 3-[2-[[(2-Methoxyphenyl)methyl]amino]ethyl]-2,4(1H,3H)-quinazolinedione; 3-[2-[[(2-Methoxyphenyl)Methyl]Amino]Ethyl]-2,4(1H,3H)Quinazolinedione
  • PSA 76.38000
  • LogP 2.29140

3-[2-[[(2-Methoxyphenyl)methyl]amino]ethyl]-2,4(1H,3H)-quinazolinedione Specification

 RH-34 is a compound which acts as a potent and selective partial agonist for the 5-HT2A serotonin receptor subtype. It was derived by structural modification of the selective 5-HT2A antagonist ketanserin, with the 4-(p-fluorobenzoyl)piperidine moiety replaced by the N-(2-methoxybenzyl) pharmacophore found in such potent 5-HT2A agonists as NBOMe-2C-B and NBOMe-2C-I. This alteration was found to retain 5-HT2A affinity and selectivity, but reversed activity from an antagonist to a moderate efficacy partial agonist.

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