3,5-Dichloroanthranilic acid

This chemical is called Benzoic acid, 2-amino-3,5-dichloro-, and its systematic name is 2-amino-3,5-dichlorobenzoic acid. With the molecular formula of C₇H₅Cl₂NO₂, its molecular weight is 206.03. The CAS registry number of this chemical is 2789-92-6. Additionally, its product categories are Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts.

Other characteristics of the Benzoic acid, 2-amino-3,5-dichloro- can be summarised as followings: (1)ACD/LogP: 3.84; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.19; (4)ACD/LogD (pH 7.4): 0.83; (5)ACD/BCF (pH 5.5): 10.83; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 64.96; (8)ACD/KOC (pH 7.4): 2.87; (9)#H bond acceptors: 3; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 29.54 Å²; (13)Index of Refraction: 1.658; (14)Molar Refractivity: 47.2 cm³; (15)Molar Volume: 128.1 cm³; (16)Polarizability: 18.71×10^-24cm³; (17)Surface Tension: 67.2 dyne/cm; (18)Density: 1.607 g/cm³; (19)Flash Point: 162.1 °C; (20)Enthalpy of Vaporization: 62.1 kJ/mol; (21)Boiling Point: 344.4 °C at 760 mmHg; (22)Vapour Pressure: 2.51E-05 mmHg at 25°C.

Production method of this chemical: The Benzoic acid, 2-amino-3,5-dichloro- could be obtained by the reactant of 2-amino-benzoic acid. This reaction needs the reagents of diethyl ether, sulfuryl chloride.

Uses of this chemical: The Benzoic acid, 2-amino-3,5-dichloro- could react with 1-chloro-4-phenyl-phthalazine, and obtain the 9,11-dichloro-5-phenyl-6,6a,12-triaza-benzo[a]anthracen-7-one. This reaction should be taken for 4 hours at the temperature of 150-160 °C. The yield is 60 %.

When you are using this chemical, please be cautious about it as the following: This chemical is irritating to eyes, respiratory system and skin. You should wear suitable protective clothing if you use it. In case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
1.SMILES: Clc1cc(Cl)cc(C(=O)O)c1N
2.InChI: InChI=1/C7H5Cl2NO2/c8-3-1-4(7(11)12)6(10)5(9)2-3/h1-2H,10H2,(H,11,12)
3.InChIKey: KTHTXLUIEAIGCD-UHFFFAOYAF

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	oral	1320mg/kg (1320mg/kg)	BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 52(6), Pg. 85, 1987.
mouse	LDLo	intraperitoneal	500mg/kg (500mg/kg)		"Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 5, Pg. 284, 1953.
rat	LD50	oral	4120mg/kg (4120mg/kg)	BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 52(6), Pg. 85, 1987.