Product Name

  • Name

    4'-(Chloroacetyl)-acetanilide

  • EINECS 205-416-8
  • CAS No. 140-49-8
  • Article Data12
  • CAS DataBase
  • Density 1.279 g/cm3
  • Solubility Insoluble in water
  • Melting Point 216-219 °C(lit.)
  • Formula C10H10ClNO2
  • Boiling Point 432.48 °C at 760 mmHg
  • Molecular Weight 211.648
  • Flash Point 215.357 °C
  • Transport Information
  • Appearance Odorless yellow-orange solid or brown powder
  • Safety 26-36
  • Risk Codes 36/37/38
  • Molecular Structure Molecular Structure of 140-49-8 (4'-(Chloroacetyl)-acetanilide)
  • Hazard Symbols IrritantXi
  • Synonyms Acetamide,N-[4-(chloroacetyl)phenyl]- (9CI);Acetanilide, 4'-(chloroacetyl)-(6CI,7CI,8CI);1-Acetamido-4-chloroacetylbenzene;1-Acetylamino-4-chloroacetylbenzene;4-Acetamidophenacyl chloride;4-Acetylaminophenacyl chloride;NSC 768;p-(Acetylamino)phenacyl chloride;p-Acetamidophenacyl chloride;
  • PSA 46.17000
  • LogP 2.13950

4'-(Chloroacetyl)-acetanilide Chemical Properties

IUPAC Name: 4'-(Chloroacetyl)-acetanilide
The MF of 4'-(Chloroacetyl)-acetanilide (140-49-8) is C10H10ClNO2.

                             
The MW of 4'-(Chloroacetyl)-acetanilide (140-49-8) is 211.64.
Synonyms of 4'-(Chloroacetyl)-acetanilide (140-49-8): 4'-(Chloracetyl)acetanilide ; Acetamide, N-[4-(2-chloroacetyl)phenyl]- ; p-Chloroacetoacetanilide
Form: Odorless yellow-orange solid or brown powder
Product Categories: ACETYLHALIDE
Index of Refraction: 1.584 
Density: 1.279 g/ml 
Flash Point: 215.4 °C 
Boiling Point: 432.5 °C
Melting Poing: 216-219 °C
Water Solubility: Insoluble

4'-(Chloroacetyl)-acetanilide Toxicity Data With Reference

1.    

mmo-sat 3300 ng/plate

     ENMUDM    Environmental Mutagenesis. 7 (Suppl 5)(1985),1.
2.    

orl-rat LD50:2150 mg/kg

     NCILB*    Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. (Bethesda, MD) NIH-NCI-E-C-72-3252 .
3.    

orl-mus LD50:1470 mg/kg

     NCILB*    Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. (Bethesda, MD) NIH-NCI-E-C-72-3252 .

4'-(Chloroacetyl)-acetanilide Consensus Reports

NCI Carcinogenesis Bioassay (feed); No Evidence: mouse, rat NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-177 ,1979. . Reported in EPA TSCA Inventory.

4'-(Chloroacetyl)-acetanilide Safety Profile

Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits very toxic fumes of Cl− and NOx. See also CHLORIDES.
Safety information of 4'-(Chloroacetyl)-acetanilide (140-49-8):
Hazard Codes  Xi
Risk Statements 
36/37/38  Irritating to eyes, respiratory system and skin 
Safety Statements 
26  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36  Wear suitable protective clothing
WGK Germany  2
RTECS  AE1050000

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