• Name

  2,3-Dibromo-5-benzoylpyrrole

• EINECS
• CAS No. 50372-61-7
• Article Data5
• CAS DataBase
• Density 1.846 g/cm³
• Solubility
• Melting Point
• Formula C₁₁H₇Br₂NO
• Boiling Point 430.963 °C at 760 mmHg
• Molecular Weight 328.991
• Flash Point 214.439 °C
• Transport Information
• Appearance
• Safety
• Risk Codes
• Molecular Structure
• Hazard Symbols
• Synonyms (4,5-Dibromo-1H-pyrrol-2-yl)(phenyl)methanone;2,3-Dibromo-5-benzoylpyrrole;4,5-Dibromo-2-benzoylpyrrole;
• PSA 32.86000
• LogP 3.77070

Synthetic route

7697-46-3

phenyl(1H-pyrrol-2-yl)methanone

50372-61-7

2,3-dibromo-5-benzoylpyrrole

Conditions

Conditions	Yield
With copper(ll) bromide In acetonitrile for 48h; Ambient temperature;	85%
With bromine In dichloromethane 0 deg C to RT, 2.5 h;	77%
With bromine In dichloromethane	76.5%

5617-70-9

cycl-isopropylidene cyclopropane-1,1-dicarboxylate

50372-61-7

2,3-dibromo-5-benzoylpyrrole

80965-17-9

C19H16Br2NO5(1-)*Na(1+)

Conditions

Conditions	Yield
With sodium hydride 1.) DMF, RT, 1 h, 2.) 75-80 deg C, 4 h; Multistep reaction;

50372-61-7

2,3-dibromo-5-benzoylpyrrole

74103-06-3

Ketorolac

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 1.) NaH / 1.) DMF, RT, 1 h, 2.) 75-80 deg C, 4 h 2: HCl / 5 h / 0 deg C to RT 4: magnesium oxide, H2 / 5percent Pd/C / H2O; methanol / 2 h / 760 Torr / Ambient temperature View Scheme

50372-61-7

2,3-dibromo-5-benzoylpyrrole

84023-60-9

5-benzoyl-7-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 1.) NaH / 1.) DMF, RT, 1 h, 2.) 75-80 deg C, 4 h 2: HCl / 5 h / 0 deg C to RT View Scheme

50372-61-7

2,3-dibromo-5-benzoylpyrrole

80965-19-1

methyl 5-benzoyl-7-bromo-1,2-dihydro-3H-pyrrolo<1,2-a>pyrrole-1-carboxylate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 1.) NaH / 1.) DMF, RT, 1 h, 2.) 75-80 deg C, 4 h 2: HCl / 5 h / 0 deg C to RT 3: 1.) NaH / 1.) DMF, 20 min, 2.) 75 deg C, 1.5 h View Scheme

50372-61-7

2,3-dibromo-5-benzoylpyrrole

80965-20-4

dimethyl 5-benzoyl-7-bromo-1,2-dihydro-3H-pyrrolo<1,2-a>pyrrole-1,1-dicarboxylate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 1.) NaH / 1.) DMF, RT, 1 h, 2.) 75-80 deg C, 4 h 2: HCl / 5 h / 0 deg C to RT 3: 1.) NaH / 1.) DMF, 20 min, 2.) 75 deg C, 1.5 h View Scheme

50372-61-7

2,3-dibromo-5-benzoylpyrrole

80965-18-0

dimethyl[2-(2,3-dibromo-5-benzoylpyrrol-1-yl)ethyl]malonate

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 1.) NaH / 1.) DMF, RT, 1 h, 2.) 75-80 deg C, 4 h 2: HCl / 5 h / 0 deg C to RT View Scheme

spiro[2.5]-5,7-dioxa-6,6-dimethyloctane-4,8-dione

spiro[2.5]-5,7-dioxa-6,6-dimethyloctane-4,8-dione

flurosil

flurosil

50372-61-7

2,3-dibromo-5-benzoylpyrrole

80965-18-0

dimethyl[2-(2,3-dibromo-5-benzoylpyrrol-1-yl)ethyl]malonate

Conditions

Conditions	Yield
With hydrogenchloride In N-methyl-acetamide; methanol; diethyl ether; mineral oil

...Expand

4,5-Dibromo-2-benzoylpyrrole Specification