• Name

  4,6-Dichloro-2-methylpyrimidine

• EINECS 605-815-0
• CAS No. 1780-26-3
• Article Data20
• CAS DataBase
• Density 1.404 g/cm³
• Solubility
• Melting Point 41.5-45.5 °C(lit.)
• Formula C₅H₄Cl₂N₂
• Boiling Point 210.8 °C at 760 mmHg
• Molecular Weight 163.006
• Flash Point 101.1 °C
• Transport Information UN 3261 8/PG 2
• Appearance white or offwhite crystalline powder
• Safety 26-36/37/39-45
• Risk Codes 34
• Molecular Structure
• Hazard Symbols C
• Synonyms 2-Methyl-4,6-dichloropyrimidine;NSC 35923;
• PSA 25.78000
• LogP 2.09180

Synthetic route

1194-22-5

2-methyl-4,6-dihydroxypyrimidine

1780-26-3

2,4-dichloro-2-methylpyrimidine

Conditions

Conditions	Yield
With trichlorophosphate Heating;	97%
With thionyl chloride In acetonitrile at 80℃; for 3h; Temperature; Concentration; Reagent/catalyst; Industrial scale;	94%
With trichlorophosphate at 95℃; for 18h;	90%

40497-30-1

2-methyl-1H-pyrimidine-4,6-dione

1780-26-3

2,4-dichloro-2-methylpyrimidine

Conditions

Conditions	Yield
With trichlorophosphate
With N,N-dimethyl-aniline; trichlorophosphate

4,6-Dichloro-2-methyl-1,2-dihydro-pyrimidine

1780-26-3

2,4-dichloro-2-methylpyrimidine

Conditions

Conditions	Yield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In tetrahydrofuran; diethyl ether for 0.0833333h; Ambient temperature; Yield given;

1780-26-3

2,4-dichloro-2-methylpyrimidine

Conditions

Conditions	Yield
With ammonia In methanol at 50℃; for 5h; Solvent; Temperature; Concentration; Industrial scale;	92%
With ammonium hydroxide In ethanol at 140℃; for 1h; Microwave irradiation;	90%
With ammonia In water; isopropyl alcohol regioselective reaction;	83%

4,6-dichloro-2-methylpyrimidine Chemical Properties

Synonyms: BUTTPARK 52\14-70;2-MDCP;2-METHYL-4,6-DICHLOROPYRIMIDINE;4,6-DICHLORO-2-METHYLPYRIMIDINE;4,6-Dichloro-2-methylpyrimidiine;Pyrimidine, 4,6-dichloro-2-methyl-;4,6-Dichloro-2-methylpyrimidine ,99%;4,6-Dichloro-2-Methylpyrimidine/2,4-dichloro-6-methylpyrimidine
The Molecular formula of 4,6-DICHLORO-2-METHYLPYRIMIDINE(1780-26-3): C₅H₄Cl₂N₂
The Molecular Weight of 4,6-DICHLORO-2-METHYLPYRIMIDINE(1780-26-3):163
Molecular Structure :  
Flash point:208 °F

4,6-dichloro-2-methylpyrimidine Safety Profile

Hazard Codes 4,6-DICHLORO-2-METHYLPYRIMIDINE(1780-26-3):  C
Risk Statements  4,6-DICHLORO-2-METHYLPYRIMIDINE(1780-26-3):
34:  Causes burns 
Safety Statements  4,6-DICHLORO-2-METHYLPYRIMIDINE(1780-26-3):
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) 
36/37/39:  Wear suitable protective clothing, gloves and eye/face protection 
RIDADR:UN 3261 8/PG 2
WGK Germany:3
HazardClass:8
PackingGroup:III