Benzeneacetic acid,2,4-dichloro-, ethyl ester supplier

Name
ETHYL 2,4-DICHLOROPHENYL ACETATE
EINECS 1533716-785-6
CAS No. 41022-54-2
Article Data7
CAS DataBase
Density 1.266 g/cm³
Solubility
Melting Point
Formula C₁₀H₁₀Cl₂O₂
Boiling Point 300.3 °C at 760 mmHg
Molecular Weight 233.094
Flash Point 121.8 °C
Transport Information
Appearance
Safety
Risk Codes
Molecular Structure
Hazard Symbols Xi
Synonyms (2,4-Dichlorophenyl)aceticacid ethyl ester;Ethyl 2,4-dichlorophenylacetate;Ethyl2-(2,4-dichlorophenyl)acetate;NSC 33951;Butyric acid, 2,4-dichlorophenyl ester;Butanoic acid, 2,4-dichlorophenyl ester;2,4-dichlorophenyl butyrate;
PSA 26.30000
LogP 3.09900

Synthetic route

: 64-17-5
ethanol

: 19719-28-9
2,4-dichlorophenylacetic acid

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

Conditions

Conditions	Yield
With sulfuric acid In benzene	95%
With sulfuric acid In benzene Reflux;

: 14062-24-9
4-chloro-benzeneacetic acid, ethyl ester

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

Conditions

Conditions	Yield
With sodium persulfate; N-chloro-succinimide; trifluorormethanesulfonic acid; palladium diacetate In 1,2-dichloro-ethane at 70℃; for 7h; Sealed tube; regioselective reaction;	66%

: 64-17-5
ethanol

: 201230-82-2
carbon monoxide

: 59293-67-3
2,4-dichlorobenzyl mercaptan

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

Conditions

Conditions	Yield
With dicobalt octacarbonyl; water at 190℃; under 43957.6 - 46543.3 Torr; for 24h;	25%

...Expand

: 41022-55-3
ethyl α-bromo-2,4-dichlorophenylacetate

A: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

B: 129430-58-6, 129430-59-7
2,3-Bis-(2,4-dichloro-phenyl)-succinic acid diethyl ester

Conditions

Conditions	Yield
In N,N-dimethyl-formamide Ambient temperature; electrolysis;

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 41022-55-3
ethyl α-bromo-2,4-dichlorophenylacetate

Conditions

Conditions	Yield
With N-Bromosuccinimide In tetrachloromethane for 5h; Irradiation;	98.7%

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 105-58-8
Diethyl carbonate

: 111544-93-5
diethyl 2-(2,4-dichlorophenyl)propanedioate

Conditions

Conditions	Yield
With sodium hydride In toluene at 20 - 100℃; for 1h; Inert atmosphere;	78%

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 98-95-3
nitrobenzene

: 855194-85-3
(2,4-dichlorophenyl)(4-nitrophenyl)methanone

Conditions

Conditions	Yield
With potassium tert-butylate In benzene at 20℃; regiospecific reaction;	68%

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

A: 5-hydroxy-2,4,6-tris(2,4-dichlorophenyl)-1,3-phenylene bis(dihydrogen phosphate)

B: 2,4,6-tris(2,4-dichlorophenyl)benzene-1,3,5-triyl tris(dihydrogen phosphate)

Conditions

Conditions	Yield
With phosphorus pentoxide at 130℃; for 0.833333h;	A 64% B 10%
With pyrophosphoric acid at 130℃; for 0.833333h;	A n/a B 64%
With phosphorus pentoxide at 130℃; for 0.916667h;	A 52% B 16%
With pyrophosphoric acid at 130℃; for 0.833333h;

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 383-63-1
ethyl trifluoroacetate,

: ethyl 2-(2,4-dichlorophenyl)-4,4,4-trifluoro-3-oxobutanoate

Conditions

Conditions	Yield
With sodium In diethyl ether for 12h; Reflux;	7%

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 4360-47-8
cinnamonitrile

: 134823-36-2, 134823-37-3
2-(2,4-dichlorophenyl)-4-cyano-3-phenylbutanoate d'ethyle threo

: 134823-36-2, 134823-37-3
2-(2,4-dichlorophenyl)-4-cyano-3-phenylbutanoate d'ethyle erythro

Conditions

Conditions	Yield
With sodium amide 1.) Et2O, -5 deg C, 2.) a) Et2O, -5 deg C, 3 h, b) 15 deg C, 3 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
With sodium amide 1.) Et2O, -5 deg C, 2.) a) Et2O, -5 deg C, 3 h, b) 15 deg C, 3 h; Yield given. Multistep reaction. Yields of byproduct given;

...Expand

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 129430-58-6, 129430-59-7
2,3-Bis-(2,4-dichloro-phenyl)-succinic acid diethyl ester

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 98.7 percent / NBS / CCl4 / 5 h / Irradiation 2: dimethylformamide / Ambient temperature; electrolysis View Scheme

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 902170-69-8
2-(2,4-Dichlorophenyl)-1-pyridin-4-yl-1-ethanone

Conditions

Conditions	Yield
Stage #1: ethyl 2-(2, 4-dichlorophenyl)acetate With lithium diisopropyl amide In tetrahydrofuran at -60℃; for 0.333333h; Stage #2: ethyl 2-(2, 4-dichlorophenyl)acetate In tetrahydrofuran at 20℃; for 20h; Stage #3: With hydrogenchloride; sodium hydrogencarbonate more than 3 stages;

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 95-92-1
oxalic acid diethyl ester

: 1188446-43-6
diethyl 2-(2,4-dichlorophenyl)-3-oxosuccinate

Conditions

Conditions	Yield
With sodium ethanolate In ethanol; mineral oil at 70℃; for 2h;

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 2,4-dichlorophenylacetylhydrazide

Conditions

Conditions	Yield
With hydrazine hydrate In ethanol Reflux;
With hydrazine hydrate at 80℃; for 6h;

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 1023575-67-8
2-mercapto-5-(2,4-dichlorobenzyl)-1,3,4-oxadiazole

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: hydrazine hydrate / 6 h / 80 °C 2.1: carbon disulfide; potassium hydroxide / diethyl ether; ethanol / 16 h / 20 °C 2.2: 20 h / 65 °C View Scheme

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 4-(2,4-dichlorophenyl)-1,2-tetramethylene-5-trifluoromethyl-4-pyrazolin-3-one

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium / diethyl ether / 12 h / Reflux 2: triethylamine / 1,4-dioxane / 2 h / Reflux View Scheme

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 1188446-44-7
ethyl 3-(2,4-dichlorophenyl)-2-oxopropanoate

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium ethanolate / ethanol; mineral oil / 2 h / 70 °C 2: water; sodium chloride / dimethyl sulfoxide / 1 h / 120 °C View Scheme

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 1188446-46-9
ethyl 5-(2,4-dichlorophenyl)-1,2,3-thiadiazole-4-carboxylate

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: sodium ethanolate / ethanol; mineral oil / 2 h / 70 °C 2: water; sodium chloride / dimethyl sulfoxide / 1 h / 120 °C 3: toluene / 5 h / 100 °C 4: thionyl chloride / 18 h / 60 °C View Scheme

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 1188446-45-8
ethyl 2-(3-(2,4-dichlorophenyl)-1-ethoxy-1-oxopropan-2-ylidene)hydrazinecarboxylate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: sodium ethanolate / ethanol; mineral oil / 2 h / 70 °C 2: water; sodium chloride / dimethyl sulfoxide / 1 h / 120 °C 3: toluene / 5 h / 100 °C View Scheme

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 2-(2,4-dichlorophenyl)propane-1,3-diol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium hydride / toluene / 1 h / 20 - 100 °C / Inert atmosphere 2: lithium aluminium tetrahydride / tetrahydrofuran; diethyl ether / 8 h / 0 - 20 °C / Inert atmosphere View Scheme

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: [2-(2,4-dichlorophenyl)-3-methylsulfonyloxy-propyl] methanesulfonate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: sodium hydride / toluene / 1 h / 20 - 100 °C / Inert atmosphere 2: lithium aluminium tetrahydride / tetrahydrofuran; diethyl ether / 8 h / 0 - 20 °C / Inert atmosphere 3: triethylamine / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere View Scheme

: 41022-54-2
ethyl 2-(2, 4-dichlorophenyl)acetate

: 2-[5-(2,4-dichlorophenyl)-1,3-dithian-2-ylidene]-2-imidazol-1-ylacetonitrile

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1.1: sodium hydride / toluene / 1 h / 20 - 100 °C / Inert atmosphere 2.1: lithium aluminium tetrahydride / tetrahydrofuran; diethyl ether / 8 h / 0 - 20 °C / Inert atmosphere 3.1: triethylamine / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere 4.1: potassium hydroxide / dimethyl sulfoxide / 10 - 20 °C / Inert atmosphere 4.2: 20 °C / Inert atmosphere View Scheme

Yield

Multi-step reaction with 4 steps
1.1: sodium hydride / toluene / 1 h / 20 - 100 °C / Inert atmosphere
2.1: lithium aluminium tetrahydride / tetrahydrofuran; diethyl ether / 8 h / 0 - 20 °C / Inert atmosphere
3.1: triethylamine / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere
4.1: potassium hydroxide / dimethyl sulfoxide / 10 - 20 °C / Inert atmosphere
4.2: 20 °C / Inert atmosphere
View Scheme

Benzeneacetic acid,2,4-dichloro-, ethyl ester Specification

The Benzeneacetic acid,2,4-dichloro-, ethyl ester, with the CAS registry number 41022-54-2, has the systematic name of 2,4-dichlorophenyl butanoate. And the molecular formula of this chemical is C₁₀H₁₀Cl₂O₂. It is a kind of irritant chemical, and should be stored in the dry and cool environment.

The physical properties of Benzeneacetic acid,2,4-dichloro-, ethyl ester are as following: (1)ACD/LogP: 3.71; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 2; (4)#H bond donors: 0; (5)#Freely Rotating Bonds: 4; (6)Polar Surface Area: 26.3 Å²; (7)Index of Refraction: 1.527; (8)Molar Refractivity: 56.64 cm³; (9)Molar Volume: 183.9 cm³; (10)Polarizability: 22.45×10^-24cm³; (11)Surface Tension: 39.1 dyne/cm; (12)Density: 1.266 g/cm³; (13)Flash Point: 121.8 °C; (14)Enthalpy of Vaporization: 54.03 kJ/mol; (15)Boiling Point: 300.3 °C at 760 mmHg; (16)Vapour Pressure: 0.00113 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES: Clc1cc(Cl)ccc1OC(=O)CCC
(2)InChI: InChI=1/C10H10Cl2O2/c1-2-3-10(13)14-9-5-4-7(11)6-8(9)12/h4-6H,2-3H2,1H3
(3)InChIKey: ZVLYZDINTHKGLR-UHFFFAOYAD

Product Name

ETHYL 2,4-DICHLOROPHENYL ACETATE

Synthetic route

Benzeneacetic acid,2,4-dichloro-, ethyl ester Specification

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