Product Name

  • Name

    ufenamate

  • EINECS
  • CAS No. 67330-25-0
  • Density 1.22g/cm3
  • Solubility
  • Melting Point
  • Formula C18H18 F3 N O2
  • Boiling Point 394.3oC at 760 mmHg
  • Molecular Weight 337.342
  • Flash Point 192.2oC
  • Transport Information
  • Appearance
  • Safety Moderately toxic by ingestion and other routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of F− and NOx. See also ESTERS.
  • Risk Codes
  • Molecular Structure Molecular Structure of 67330-25-0 (ufenamate)
  • Hazard Symbols
  • Synonyms Butylflufenamate; Combec; Fenazol; Flufenamic acid butyl ester; HF 264; Ufenamate
  • PSA 38.33000
  • LogP 5.47890

Synthetic route

n-Butyl N-(3-trifluoromethylphenyl)anthranilate
67330-25-0

n-Butyl N-(3-trifluoromethylphenyl)anthranilate

2-(2-(3-trifluoromethylphenylamino)-phenyl)-2-imidazoline
83265-70-7

2-(2-(3-trifluoromethylphenylamino)-phenyl)-2-imidazoline

Conditions
ConditionsYield
With ethylenediamine In methanol30%

Butyl Flufenamate Chemical Properties

Chemistry informtion about Butyl Flufenamate(CAS NO.67330-25-0) is:
IUPAC Name: butyl 2-[3-(trifluoromethyl)anilino]benzoate
Synonyms: Ufenamate ; Butyl Flufenamate ; 2-[[3-(Trifluoromethyl)Phenyl]Amino]Benzoic Acid Butyl Ester ; Butyl Fulfenamate ; Hf-264 ; O-(M-Trifluoromethylanilino)Benzoic Acid Butyl Ester
Molecular Weight: 337.33623 [g/mol]
Molecular Formula: C18H18F3NO2
XLogP3: 6.8
H-Bond Donor: 1
H-Bond Acceptor: 6
EINECS: 207-332-7 
Density: 1.22 g/cm3
Flash Point: 192.2 °C
Enthalpy of Vaporization: 64.43 kJ/mol
Boiling Point: 394.3 °C at 760 mmHg
Vapour Pressure: 2.01E-06 mmHg at 25°C
Following is the molecular structure of Butyl Flufenamate(CAS NO.67330-25-0) is:

 

Butyl Flufenamate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intraperitoneal 1500mg/kg (1500mg/kg) BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: MUSCLE WEAKNESS

GASTROINTESTINAL: NAUSEA OR VOMITING		 Oyo Yakuri. Pharmacometrics. Vol. 18, Pg. 845, 1979.
dog LD50 oral > 16gm/kg (16000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 18, Pg. 845, 1979.
dog LD50 skin > 1gm/kg (1000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 18, Pg. 845, 1979.
dog LD50 subcutaneous 9300mg/kg (9300mg/kg) BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: MUSCLE WEAKNESS

GASTROINTESTINAL: NAUSEA OR VOMITING		 Oyo Yakuri. Pharmacometrics. Vol. 18, Pg. 845, 1979.
mouse LD50 intraperitoneal 4100mg/kg (4100mg/kg) BEHAVIORAL: ANTIPSYCHOTIC

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

SKIN AND APPENDAGES (SKIN): HAIR: OTHER		 Oyo Yakuri. Pharmacometrics. Vol. 18, Pg. 845, 1979.
mouse LD50 intravenous 610mg/kg (610mg/kg) BEHAVIORAL: ANTIPSYCHOTIC

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Oyo Yakuri. Pharmacometrics. Vol. 18, Pg. 845, 1979.
mouse LD50 oral 3100mg/kg (3100mg/kg) BEHAVIORAL: ANTIPSYCHOTIC

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

SKIN AND APPENDAGES (SKIN): HAIR: OTHER		 Oyo Yakuri. Pharmacometrics. Vol. 18, Pg. 845, 1979.
mouse LD50 skin > 3gm/kg (3000mg/kg)   Drugs in Japan Vol. -, Pg. 160, 1990.
mouse LD50 subcutaneous > 10gm/kg (10000mg/kg)   Drugs in Japan Vol. -, Pg. 160, 1990.
rabbit LD50 intraperitoneal 11500mg/kg (11500mg/kg) BEHAVIORAL: ANTIPSYCHOTIC

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"		 Oyo Yakuri. Pharmacometrics. Vol. 18, Pg. 845, 1979.
rabbit LD50 oral 4800mg/kg (4800mg/kg) BEHAVIORAL: ANTIPSYCHOTIC

SKIN AND APPENDAGES (SKIN): HAIR: OTHER

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"		 Oyo Yakuri. Pharmacometrics. Vol. 18, Pg. 845, 1979.
rabbit LD50 skin > 4gm/kg (4000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 18, Pg. 845, 1979.
rabbit LD50 subcutaneous > 10gm/kg (10000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 18, Pg. 845, 1979.
rat LD50 intraperitoneal 4550mg/kg (4550mg/kg) BEHAVIORAL: ANTIPSYCHOTIC

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

SKIN AND APPENDAGES (SKIN): HAIR: OTHER		 Oyo Yakuri. Pharmacometrics. Vol. 18, Pg. 845, 1979.
rat LD50 intravenous 650mg/kg (650mg/kg) BEHAVIORAL: ANTIPSYCHOTIC

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"		 Oyo Yakuri. Pharmacometrics. Vol. 18, Pg. 845, 1979.
rat LD50 oral 510mg/kg (510mg/kg) BEHAVIORAL: ANTIPSYCHOTIC

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

SKIN AND APPENDAGES (SKIN): HAIR: OTHER		 Oyo Yakuri. Pharmacometrics. Vol. 18, Pg. 845, 1979.
rat LD50 skin > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. -, Pg. 160, 1990.
rat LD50 subcutaneous > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. -, Pg. 197, 1995.

Butyl Flufenamate Safety Profile

Moderately toxic by ingestion and other routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of F− and NOx. See also ESTERS.

Butyl Flufenamate Specification

Descriptors Computed from Structure about Butyl Flufenamate(CAS NO.67330-25-0) is:
Canonical SMILES: CCCCOC(=O)C1=CC=CC=C1NC2=CC=CC(=C2)C(F)(F)F
InChI: InChI=1S/C18H18F3NO2/c1-2-3-11-24-17(23)15-9-4-5-10-16(15)22-14-8-6-7-13(12-14)18(19,20)21/h4-10,12,22H,2-3,11H2,1H3
InChIKey: JDLSRXWHEBFHNC-UHFFFAOYSA-N

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