Product Name

  • Name

    Ethyl 2-hydroxyisobutyrate

  • EINECS 201-290-3
  • CAS No. 80-55-7
  • Article Data20
  • CAS DataBase
  • Density 1.027 g/cm3
  • Solubility
  • Melting Point 78 °C
  • Formula C6H12O3
  • Boiling Point 152.1 °C at 760 mmHg
  • Molecular Weight 132.159
  • Flash Point 44.4 °C
  • Transport Information UN 3272 3/PG 3
  • Appearance clear colorless liquid
  • Safety 26-36-16
  • Risk Codes 10-36/37/38-36/38
  • Molecular Structure Molecular Structure of 80-55-7 (Ethyl 2-hydroxyisobutyrate)
  • Hazard Symbols IrritantXi
  • Synonyms Ethyl a-hydroxyisobutyrate;NSC 4667;2-Hydroxy-2-methylpropanoic acidethyl ester;2-Hydroxyisobutyricacid ethyl ester;Ethyl2-hydroxy-2-methylpropionate;
  • PSA 46.53000
  • LogP 0.32040

ETHYL 2-HYDROXYISOBUTYRATE Chemical Properties

1.IUPAC Name:  Ethyl 2-hydroxy-2-methylpropanoate
2.Synonyms:  2-Hydroxy-2-methyl-propanoicaciethylester ; 2-Hydroxyisobutyricacidethylester(alpha-) ; 2-Methyl-lacticaciethylester ; Ethyl 2-hydroxy-2-methylpropanoate ; Ethyl2-hydroxy-2-methylpropanoate ; Lactic acid 2-methyl-ethyl ester ; Ethyl 2-methyllactate ; Ethly 2-hydroxyisobuyrate
3.The Molecular Formula of  Ethyl 2-hydroxyisobutyrate (80-55-7) : C6H12O3
4.The Molecular Weight of  Ethyl 2-hydroxyisobutyrate (80-55-7) : 132.16g/mol
5.The Molecular Structure of  Ethyl 2-hydroxyisobutyrate (80-55-7) :
6.Density: 0.965 g/mL at 25 °C(lit.)
7.Boiling Point: 150 °C(lit.)
8.Flash Point: 112 °F
9.Storage Condition: keep away from heat, sparksand flame.
10.Refractive Index (nD): 1.408(lit.)
11.Appearance: clear colorless liquid
12.Solubility: insoluble in water ,but soluble in alcohol , ether

ETHYL 2-HYDROXYISOBUTYRATE Uses

1.  Ethyl 2-hydroxyisobutyrate  (80-55-7) is Mainly used to produce  5, 5-Dimethyl-2, 4-oxazolidinedione ,  Ethadione ,  Trimethadione  etc.
2.It can be used as pharmaceutical intermediate and take part in many organic syntheses.

ETHYL 2-HYDROXYISOBUTYRATE Toxicity Data With Reference

1.    

ims-gpg LDLo:2200 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 76 (1942),189.

ETHYL 2-HYDROXYISOBUTYRATE Safety Profile

Moderately toxic by intramuscular route. When heated to decomposition it emits acrid smoke and irritating vapors.
 Hazard Codes:  Xi
Risk Statements:  10-36/37/38-36/38
R10:  Flammable
R36/37/38:  Irritating to eyes, respiratory system and skin
R36/38:  Irritating to eyes and skin
Safety Statements:  26-36-16
S16:  Keep away from sources of ignition.
S26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical
advice. 
S36:  Wear suitable protective clothing. 
WGK Germany:  3

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