1,1'-CARBONYLDIPIPERIDINE

The CAS registry number of Methanone,di-1-piperidinyl- is 5395-04-0. Its EINECS registry number is 226-407-5. The IUPAC name is di(piperidin-1-yl)methanone. In addition, the molecular formula is C₁₁H₂₀N₂O and the molecular weight is 196.29. What's more, it is a kind of faintly yellow crystals and belongs to the class of API Intermediates. And it should be stored in sealed container, and put in a cool and dry place.

Physical properties about this chemical are: (1)ACD/LogP: 2.20; (2)ACD/LogD (pH 5.5): 2.2; (3)ACD/LogD (pH 7.4): 2.2; (4)ACD/BCF (pH 5.5): 27.5; (5)ACD/BCF (pH 7.4): 27.5; (6)ACD/KOC (pH 5.5): 373.14; (7)ACD/KOC (pH 7.4): 373.14; (8)#H bond acceptors: 3; (9)Polar Surface Area: 23.55 Å²; (10)Index of Refraction: 1.524; (11)Molar Refractivity: 55.81 cm³; (12)Molar Volume: 182.3 cm³; (13)Polarizability: 22.12 ×10^-24cm³; (14)Surface Tension: 43.9 dyne/cm; (15)Density: 1.076 g/cm³; (16)Flash Point: 119.1 °C; (17)Enthalpy of Vaporization: 53.68 kJ/mol; (18)Boiling Point: 297 °C at 760 mmHg; (19)Vapour Pressure: 0.00139 mmHg at 25°C.

Preparation of Methanone,di-1-piperidinyl-: it can be prepared by piperidine and trimethoxyacetonitrile. The reaction time is 8 hours at reaction temperature of 100 °C. The yield is about 79%.

Uses of Methanone,di-1-piperidinyl-: it can be used to get Chlorbis(1-piperidinyl)carbenium-chlorid. This reaction will need reagent COCl₂ and solvent diethyl ether. The reaction time is 3 hours. The yield is about 92%.

When you are using this chemical, please be cautious about it as the following:
During using it, you should avoid contact with skin and eyes.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(N1CCCCC1)N2CCCCC2
(2)InChI: InChI=1/C11H20N2O/c14-11(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10H2
(3)InChIKey: SNOJOKOVTYPHMC-UHFFFAOYAT

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LDLo	intraperitoneal	500mg/kg (500mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	"Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 6, Pg. 61, 1954.