Product Name

  • Name

    Sodium 2,2,3,3-tetrafluoropropionate

  • EINECS 245-311-4
  • CAS No. 22898-01-7
  • Article Data2
  • CAS DataBase
  • Density
  • Solubility
  • Melting Point
  • Formula C3HF4NaO2
  • Boiling Point 140.7 °C at 760 mmHg
  • Molecular Weight 168.023
  • Flash Point 38.9 °C
  • Transport Information
  • Appearance white crystals
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 22898-01-7 (Sodium 2,2,3,3-tetrafluoropropionate)
  • Hazard Symbols C
  • Synonyms Propanoicacid, 2,2,3,3-tetrafluoro-, sodium salt (9CI);Propionic acid,2,2,3,3-tetrafluoro-, sodium salt (8CI);2,2,3,3-Tetrafluoropropionic acidsodium salt;Frenock;Orga 3045;Sodium 2,2,3,3-tetrafluoropropanoate;Sodium2,2,3,3-tetrafluoropropionate;Sodium tetrafluoropropionate;TFP;Taskforce;Tetrafluoropropionic acid sodium salt;Tetrapion;
  • PSA 40.13000
  • LogP -0.36330

Synthetic route

5-amino-1,1,2,2-tetrafluoro-4-hexen-3-one
72721-34-7

5-amino-1,1,2,2-tetrafluoro-4-hexen-3-one

Na-2,2,3,3-Tetrafluoropropionate
22898-01-7

Na-2,2,3,3-Tetrafluoropropionate

Conditions
ConditionsYield
With potassium hydroxide In ethanol for 8h; Heating;
1,1,2,2-tetrafluoro-5-(N-methylamino)-hex-4-en-3-one
72721-37-0

1,1,2,2-tetrafluoro-5-(N-methylamino)-hex-4-en-3-one

A

Na-2,2,3,3-Tetrafluoropropionate
22898-01-7

Na-2,2,3,3-Tetrafluoropropionate

B

acetone
67-64-1

acetone

C

methylamine
74-89-5

methylamine

Conditions
ConditionsYield
With sodium hydroxide In ethanol at 20℃; Rate constant; Mechanism;
5-amino-1,1,2,2-tetrafluoro-4-hexen-3-one
72721-34-7

5-amino-1,1,2,2-tetrafluoro-4-hexen-3-one

A

Na-2,2,3,3-Tetrafluoropropionate
22898-01-7

Na-2,2,3,3-Tetrafluoropropionate

B

acetone
67-64-1

acetone

C

NH3

NH3

Conditions
ConditionsYield
With sodium hydroxide In ethanol at 20℃; Rate constant; Mechanism;
1,1,2,2-tetrafluoro-5-phenyl-5-amino-4-penten-3-one
123824-65-7

1,1,2,2-tetrafluoro-5-phenyl-5-amino-4-penten-3-one

A

Na-2,2,3,3-Tetrafluoropropionate
22898-01-7

Na-2,2,3,3-Tetrafluoropropionate

B

acetophenone
98-86-2

acetophenone

C

NH3

NH3

Conditions
ConditionsYield
With sodium hydroxide In ethanol at 20℃; Rate constant; Mechanism;
3,3-dimethylbutan-2-one O-(3-phenylpropyl) oxime

3,3-dimethylbutan-2-one O-(3-phenylpropyl) oxime

Na-2,2,3,3-Tetrafluoropropionate
22898-01-7

Na-2,2,3,3-Tetrafluoropropionate

acetic acid
64-19-7

acetic acid

A

C18H23F4NO3

C18H23F4NO3

B

C21H23F8NO5

C21H23F8NO5

C

C20H25F4NO5

C20H25F4NO5

Conditions
ConditionsYield
With sodium nitrate; oxygen; palladium diacetate at 100℃; for 0.666667h; Schlenk technique;A 30%
B 15%
C 19%

Sodium 2,2,3,3-tetrafluoropropionate Chemical Properties

IUPAC Name:Sodium 2,2,3,3-tetrafluoropropanoate(22898-01-7)
Synonyms: Tetrapion ; Sodium 2,2,3,3-tetrafluoropropionate ; Flupropanate sodium ; 2,2,3,3-Tetrafluoropropionic acid sodium ; Flupropion ; Orga-3045 ; Tetrapion sodium ; 2,2,3,3-Tetrafluoropropionic acid, Sodium salt
Mol File: 22898-01-7.mol
Molecular Structure of Sodium tetrafluoropropionate (22898-01-7) : 
Molecular Formula of Sodium tetrafluoropropionate (22898-01-7)  :  C3HF4NaO2
Molecular Weight:  168.02
CAS :  22898-01-7
EINECS : 245-311-4
Flash Point: 38.9 °C 
Enthalpy of Vaporization: 41.7 kJ/mol 
Boiling Point: 140.7 °C at 760 mmHg
Vapour Pressure: 3.47 mmHg at 25°C 

Sodium 2,2,3,3-tetrafluoropropionate Uses

The influence of Sodium tetrafluoropropionate (22898-01-7) on the growth and organ formation of callus derived from rice seedlings was examined in order to study the plant growth inhibition mechanism of this herbicide. Although a concentration of about 2 mg/l resulted in 50% growth inhibition in rice seedlings, only slight growth inhibition was observed in rice callus even at the high concentration of 1,000 mg/l. The initiation of bud differentiation was slightly inhibited by tetrapion but inhibition of development from differentiated buds to plantlets was quite remarkable. These results suggest that basal metabolisms required for life itself, growth, and the reproduction of cells are not inhibited by treatment with this herbicide, and its inhibition target is in the morphogenetic process, including the skeleton structure construction in the tissue and organs.

 

Sodium 2,2,3,3-tetrafluoropropionate Toxicity Data With Reference

 

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 9240mg/kg (9240mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 15, Pg. 489, 1973.
rabbit LD50 skin > 2gm/kg (2000mg/kg)   Japan Pesticide Information. Vol. (40), Pg. 32, 1982.
rat LD50 oral 8570mg/kg (8570mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 15, Pg. 489, 1973.


 

 

Sodium 2,2,3,3-tetrafluoropropionate Safety Profile

Hazard Codes:  C

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