• Name

  Sodium 4-aminosalicylate dihydrate

• EINECS 205-091-2
• CAS No. 6018-19-5
• Density
• Solubility Soluble in water
• Melting Point 250 °C
• Formula C₇H₁₀NNaO₅
• Boiling Point 380.8 °C at 760 mmHg
• Molecular Weight 211.15
• Flash Point 184.1 °C
• Transport Information
• Appearance white to beige fine crystalline powder
• Safety 26-36
• Risk Codes 36/37/38
• Molecular Structure
• Hazard Symbols Xi
• Synonyms Benzoicacid, 4-amino-2-hydroxy-, monosodium salt, dihydrate (9CI);Salicylic acid, 4-amino-,monosodium salt, dihydrate (8CI);Monosodium p-aminosalicylate dihydrate;Sodium 4-amino-2-hydroxybenzoate dihydrate;Sodium 4-aminosalicylate dihydrate;Sodium p-aminosalicylate dihydrate;p-Aminosalicylic acid sodium salt dihydrate;
• PSA 104.84000
• LogP -0.20950

Synthetic route

6018-19-5

sodium 4-aminosalicylate dihydrate

disodium-salt

disodium-salt

Conditions

Conditions	Yield
at 164 - 165℃;

7758-89-6

copper(I) chloride

glacial HOAc

glacial HOAc

6018-19-5

sodium 4-aminosalicylate dihydrate

98273-15-5

4-chlorosulfonyl-2-hydroxy-benzoic acid

Conditions

Conditions	Yield
With aq. NaOH; sodium nitrite In tetrahydrofuran; water; acetic acid	36.32 g (64%)

...Expand

373-02-4, 14998-37-9, 33025-09-1, 94044-50-5, 98268-31-6

nickel diacetate

6018-19-5

sodium 4-aminosalicylate dihydrate

Ni(2+)*2K(1+)*2H2NC6H3(O)CO2(2-)*5H2O=K2Ni(H2NC6H3(O)CO2)2*5H2O

Conditions

Conditions	Yield
With potassium hydroxide In water pptn. within one d;
With KOH In water pptn. within one d;

nickel(II) sulfate heptahydrate

6018-19-5

sodium 4-aminosalicylate dihydrate

Ni(4-amino-2-hydroxy-benzoate)2*4H2O

Conditions

Conditions	Yield
In water
In water

nickel(II) sulfate heptahydrate

6018-19-5

sodium 4-aminosalicylate dihydrate

90-02-8

salicylaldehyde

Ni(2+)*4H(1+)*2OC6H4CHNC6H3OCOO(3-)*4H2O={Ni(OC6H4CHNC6H3(OH)COOH)2}*4H2O

Conditions

Conditions	Yield
In ethanol; water
In ethanol; water

...Expand

copper(ll) sulfate pentahydrate

6018-19-5

sodium 4-aminosalicylate dihydrate

2Na(1+)*{Cu(C7H5NO3)2}(2-)*4H2O=Na2{Cu(C7H5NO3)2}*4H2O

Conditions

Conditions	Yield
With sodium hydroxide; water In sodium hydroxide addn. of aq. NaOH to an aq. soln. of NaC7H6NO3*2H2O; addn. of an aq. soln. of CuSO4*5H2O and aq. NaOH under heating;;

6018-19-5

sodium 4-aminosalicylate dihydrate

65-49-6

4-Aminosalicylic acid

Conditions

Conditions	Yield
With sulfuric acid

Sodium 4-aminosalicylate dihydrate Chemical Properties

Sodium 4-aminosalicylate dihydrate Safety Profile

Sodium 4-aminosalicylate dihydrate Specification