Sodium stibagluconate supplier

Name
ANTIMONY SODIUM GLUCONATE
EINECS
CAS No. 16037-91-5
Density g/cm³
Solubility
Melting Point
Formula C12H20 O17 Sb2 . 9 H2 O . 3 Na
Boiling Point 673.6°Cat760mmHg
Molecular Weight 1048.91
Flash Point 375.2°C
Transport Information
Appearance
Safety Poison by intraperitoneal route. When heated to decomposition it emits toxic fumes of Sb.
Risk Codes 20/22-51/53
Molecular Structure
Hazard Symbols Xn,N
Synonyms D-Gluconicacid, 2,4:2',4'-O-(oxydistibylidyne)bis-, Sb,Sb'-dioxide, trisodium salt,nonahydrate;D-Gluconic acid, 2,4:2',4'-O-[oxybis(oxidostibylidyne)]bis-,trisodium salt, nonahydrate (9CI);Solustibosan (7CI);1,3,2-Dioxantimonane,D-gluconic acid deriv.;1,3,2-Dioxastibinane, D-gluconic acid deriv.;Antimony sodiumgluconate;D-Gluconic acid, cyclic ester with antimonic acid (H8Sb2O9) (2:1),trisodium salt, nonahydrate;Myostibin;Pentostam;Sodium stibogluconate;Solustin;Solusurmin;Solyusurmin;Stibanate;Stibanose;Stibatin;Stibinol;Stibogluconate sodium;
PSA 399.06000
LogP -8.81310

Sodium stibagluconate Chemical Properties

Product Name: Antimony sodium gluconate
Synonyms: Antimony sodium gluconate
Molecular Structure of Antimony sodium gluconate (CAS NO.16037-91-5) :
Molecular Formula of Antimony sodium gluconate (CAS NO.16037-91-5) : C₁₂H₁₈Na₃O₁₇Sb₂
Molecular Weight of Antimony sodium gluconate (CAS NO.16037-91-5) : 746.75
CAS NO: 16037-91-5
Storage temp: 2-8°C
Solubility H₂O: 1 mg/mL at ~75 °C
Appearance: pale yellow solid
Appearance: white or slightly yellow amorphous powder significantly.
Solubility: soluble in hot water, soluble in water, insoluble in ethanol or ether. Odorless.

Sodium stibagluconate Uses

Antimony sodium gluconate (CAS NO.16037-91-5) is used as anti-leishmaniasis drugs.

Sodium stibagluconate Production

Calcium gluconate substitution reaction with sodium Carbonate to generate Sodium gluconate and then use the Antimony trichloride for Antimony trichloride reaction to get Trivalent sodium antimony gluconate, and finally Oxidation by hydrogen peroxide, obtaining Antimony sodium gluconate (CAS NO.16037-91-5) .

Sodium stibagluconate Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intraperitoneal	33mg/kg (33mg/kg)	Compilation of LD50 Values of New Drugs.
mouse	LD50	subcutaneous	7747mg/kg (7747mg/kg)	Indian Journal of Pharmacy. Vol. 11, Pg. 155, 1949.
mouse	LD50	unreported	1625mg/kg (1625mg/kg)	Drugs of the Future. Vol. 18, Pg. 451, 1993.

Sodium stibagluconate Consensus Reports

Antimony and its compounds are on the Community Right-To-Know List.

Sodium stibagluconate Safety Profile

Poison by intraperitoneal route. See also ANTIMONY COMPOUNDS. When heated to decomposition it emits toxic fumes of Sb.

RIDADR 3282
WGK Germany 3
RTECS CC7930000
HazardClass 6.1(b)
PackingGroup III

Sodium stibagluconate Standards and Recommendations

OSHA PEL: TWA 0.5 mg(Sb)/m³
ACGIH TLV: TWA 0.5 mg(Sb)/m³
NIOSH REL: TWA 0.5 mg(Sb)/m³

Product Name

ANTIMONY SODIUM GLUCONATE